… have tried to tie the dysregulation of apoptosis seen in sepsis with end organ morbidity and
… a framework to describe the role of apoptosis in the pathophysiology of sepsis. APOPTOSIS …

… -receptor pairs that regulate apoptosis brings a new level of complexity to the understanding
of apoptotic cell death. It indicates that an external killer can control apoptosis in certain …

… these apoptotic cells have on surviving immune cells. This Review focuses on the role of
apoptosis in the pathophysiology of sepsis and discusses potential anti-apoptotic therapies, …

… apoptosis is also increased in patients with sepsis and correlates with the severity of the
disease. In addition, recent evidence indicates that uptake of apoptotic … of sepsis may lead to …

… mediated apoptosis, represent an attractive therapeutic target for the septic patient. In the
current review, we address the scientific rationale for modifying apoptotic pathways in sepsis …

… Accelerated apoptosis of lymphocytes has been shown to play an … role in organ dysfunction
in sepsis and techniques to suppress apoptosis have improved survival rate in sepsis models…

… Intestinal epithelial cell apoptosis has been reported in sepsis as a mechanism of organ …
the role of apoptosis-regulating proteins (bcl-2, bax, cytochrome-c, and caspase-8) in septic rats …

… role of apoptosis in sepsis and shock. More specifically, it is becoming clearer how dysregulated
apoptosis of … to ward off the lethal effects of sepsis. This appears to correlate directly with …

… in animal models of polymicrobial sepsis and clinical findings that support the hypothesis
that apoptosis in the immune system is a pathologic event in sepsis that can be a therapeutic …

… Our laboratory has examined the effect of sepsis on endothelial cell apoptosis in a rat cecal
ligation and perforation model of sepsis. Rat thoracic aortas were obtained 24 hrs after cecal …