… importance … role of the AR in prostate cancer, and integrates a discussion on how structural
information has been used to help guide rational drug design for treatment of prostate cancer. …

… -naïve prostate cancer, but prostate cancer changes AR and adapts to survive under castration
levels of androgen. … This review focuses on the functions of AR in prostate cancer and the …

… prostatic hyperplasia and prostate cancer (PCa). Androgen action is exerted through the
androgen receptor (AR), a 110-kDa member of the steroid receptor family of transcription factors…

… The majority of PCa responds to androgen ablation therapy by temporary remission. …
relapse in an androgen-refractory state. This review will address the role of androgens and other …

… : Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate
cancer risk: A population-based case-control study in China. Cancer Res 60: 5111–5116, 2000 …

… 90% of prostate cancers are dependent on androgen at initial diagnosis, and endocrine
therapy of prostate cancer is directed toward the reduction of serum androgens and inhibition of …

… the androgen receptor, and of androgen receptor structure and expression in prostate cancer.
… issue concerns the role of the androgen receptor in hormone refractory prostate cancer. At …

… and the androgen—regulated gene, prostate—specific antigen, a concept is developing
that the androgen receptor is critical for androgen—refractory prostate cancer cells. Indeed, …

… Although further investigation is needed to delineate the role of androgen receptor (AR)
variants in metastatic castration-resistant prostate cancer, advances in measurement science …

… aware of the importance of AR signaling during prostate cancer … role of steroid receptor
coactivators (SRC) in prostate cancer. The expression of SRC-1 correlates with prostate cancer …