The role of bacterial lipopolysaccharides as immune modulator in vaccine and drug development
J Arenas - … Disorders-Drug Targets (Formerly Current Drug …, 2012 - ingentaconnect.com
… The purpose of this review is to examine the progress in the generation of new LPS-based …
In conclusion, the activation of TLR4 signaling pathway by LPS plays a dual role (i) as an …
In conclusion, the activation of TLR4 signaling pathway by LPS plays a dual role (i) as an …
A journey from structure to function of bacterial lipopolysaccharides
F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
… immunological outcomes that any given LPS can raise, which is strictly … LPS research. It is
critical to address these points to complete our notions on LPS chemistry, functions, and roles, …
critical to address these points to complete our notions on LPS chemistry, functions, and roles, …
[HTML][HTML] The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology
SM Huszczynski, JS Lam, CM Khursigara - Pathogens, 2019 - mdpi.com
… We also discuss the role of LPS in facilitating biofilm formation, … functions in bacterial
physiology. This review focuses on the role of lipid A, core, and O antigen in the sensing of LPS by …
physiology. This review focuses on the role of lipid A, core, and O antigen in the sensing of LPS by …
[HTML][HTML] Targeting LPS biosynthesis and transport in gram-negative bacteria in the era of multi-drug resistance
KP Romano, DT Hung - Biochimica et Biophysica Acta (BBA)-Molecular …, 2023 - Elsevier
… multi-drug resistant bacterial infections. Despite extensive drug discovery campaigns over
… target class effective against gram-negative bacteria has become available to patients since …
… target class effective against gram-negative bacteria has become available to patients since …
Strategies to improve drug development for sepsis
MP Fink, HS Warren - Nature reviews Drug discovery, 2014 - nature.com
… Certain microbial products, such as lipopolysaccharide (LPS; … of either LPS or viable
Gram-negative bacteria. Braude and … of Gram-negative bacteria produce LPS molecules that lack …
Gram-negative bacteria. Braude and … of Gram-negative bacteria produce LPS molecules that lack …
Lipopolysaccharide as a target for the development of novel therapeutics in gram-negative bacteria
JA Yethon, C Whitfield - … Drug Targets-Infectious Disorders, 2001 - ingentaconnect.com
… regarding the structure, function, and biosynthesis of the LPS molecule, highlighting where
… by the pharmaceutical industry for drug discovery. The focus will be on the LPS from …
… by the pharmaceutical industry for drug discovery. The focus will be on the LPS from …
Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis
DD Bannerman, SE Goldblum - American Journal of …, 2003 - journals.physiology.org
… functions. One such mediator that targets the endothelium is bacterial lipopolysaccharide
(LPS) or … that is a component of the outer envelope of all gram-negative bacteria (17, 159, 176). …
(LPS) or … that is a component of the outer envelope of all gram-negative bacteria (17, 159, 176). …
Structure of bacterial lipopolysaccharides
M Caroff, D Karibian - Carbohydrate research, 2003 - Elsevier
… Bacterial lipopolysaccharides are the major components of the outer surface of Gram-negative
bacteria They are often of interest in medicine for their immunomodulatory properties. In …
bacteria They are often of interest in medicine for their immunomodulatory properties. In …
[HTML][HTML] Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis
Y Rosenfeld, Y Shai - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
… LPS determine their biological function, the susceptibility of bacteria to them, the ability of
LPS … to interfere with this activation and to neutralize LPS-induced endotoxic shock. From a …
LPS … to interfere with this activation and to neutralize LPS-induced endotoxic shock. From a …
Biosynthesis and export of bacterial lipopolysaccharides
C Whitfield, MS Trent - Annual review of biochemistry, 2014 - annualreviews.org
… gram-negative bacteria, in which they play important roles in the … Few bacteria contain
lipopolysaccharide molecules … oligosaccharide that, in some bacteria, provides an attachment …
lipopolysaccharide molecules … oligosaccharide that, in some bacteria, provides an attachment …
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