The role of cellular senescence in ageing and endocrine disease
S Khosla, JN Farr, T Tchkonia… - Nature Reviews …, 2020 - nature.com
… senescent cells or inhibitors of the senescence… cellular senescence has a causative role in
multiple diseases associated with ageing. Finally, we focus on the role of cellular senescence …
multiple diseases associated with ageing. Finally, we focus on the role of cellular senescence …
Mechanisms and functions of cellular senescence
N Herranz, J Gil - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
… factors termed the senescence-associated secretory … cellular senescence with a special
focus on their translational relevance and suitability for identifying and characterizing senescent …
focus on their translational relevance and suitability for identifying and characterizing senescent …
Paracrine roles of cellular senescence in promoting tumourigenesis
JM Gonzalez-Meljem, JR Apps, HC Fraser… - British journal of …, 2018 - nature.com
… activities of senescent cells and their role in tumourigenesis … and metastasis, cellular
reprogramming and emergence of … The evidence described here suggests cellular senescence …
reprogramming and emergence of … The evidence described here suggests cellular senescence …
The role of cellular senescence in cardiac disease: basic biology and clinical relevance
M Mehdizadeh, M Aguilar, E Thorin… - Nature Reviews …, 2022 - nature.com
… The involvement of cellular senescence in other important entities, such as cardiac … biology
of cellular senescence and discuss what is known about the role of cellular senescence and …
of cellular senescence and discuss what is known about the role of cellular senescence and …
The role of cellular senescence in skin aging
J Campisi - Journal of Investigative Dermatology Symposium …, 1998 - Elsevier
… This loss of proliferative capacity has been termed replicative or cellular senescence. This
article reviews what is known about cell senescence and its role in the aging of organs such …
article reviews what is known about cell senescence and its role in the aging of organs such …
The paradoxical role of cellular senescence in cancer
J Yang, M Liu, D Hong, M Zeng… - Frontiers in cell and …, 2021 - frontiersin.org
… role for spontaneous senescence and therapy-induced senescence (TIS), that senescence
… Cellular senescence was initially described as a physiological suppressor mechanism of …
… Cellular senescence was initially described as a physiological suppressor mechanism of …
Roles and mechanisms of cellular senescence in regulation of tissue homeostasis
N Ohtani, E Hara - Cancer science, 2013 - Wiley Online Library
… cellular biology of cellular senescence is introduced, focusing on its positive and negative
roles … thought to be the precise mechanisms of cellular and organismal homeostatic control.1 …
roles … thought to be the precise mechanisms of cellular and organismal homeostatic control.1 …
Cellular senescence: from physiology to pathology
D Muñoz-Espín, M Serrano - Nature reviews Molecular cell biology, 2014 - nature.com
… our view of cellular senescence as a trigger of tissue remodelling that acts during normal
embryonic development and upon tissue damage. To achieve this, senescent cells arrest their …
embryonic development and upon tissue damage. To achieve this, senescent cells arrest their …
Role of cellular senescence in type II diabetes
A Narasimhan, RR Flores, PD Robbins… - …, 2021 - academic.oup.com
… diabetes promote cellular senescence. Diabetes-induced cellular senescence contributes to
… Thus, type II diabetes is both a cause and consequence of cellular senescence. This review …
… Thus, type II diabetes is both a cause and consequence of cellular senescence. This review …
The role of cellular senescence and SASP in tumour microenvironment
M Takasugi, Y Yoshida, E Hara, N Ohtani - The FEBS journal, 2023 - Wiley Online Library
… senescence-associated secretory phenotype and senescent cells for cancer therapy. In this
review, we discuss the current knowledge on cellular senescence and the senescence-… roles …
review, we discuss the current knowledge on cellular senescence and the senescence-… roles …