… that DNA adducts, which have been primarily characterised in experimental studies, appear
to have similar structures in human DNA … to detect and measure DNA adducts in man. These …

… The discovery by the Millers and their colleagues of the role of metabolism in carcinogen …
cellular macromolecules, such as DNA (3, 4). Today, DNA adduct formation is recognized as a …

… on the determination of DNA adducts by mass spectrometry that … of DNA adducts by other
techniques and also highlight the limitations associated with the interpretation of DNA adduct …

In this review, a mechanism of estrogen-induced cancer has been examined which features
a dual role of estrogen as hormone and carcinogen. Evidence exists that estrogens are …

… The role of polymerase η in accurate bypass of cisplatin adducts was inferred from the … not
possible to evaluate the role of polymerase η in the bypass of oxaliplatin adducts in this study. …

… However, thanks to recent analytical advances in the detection of low levels of DNA adducts,
it is now evident that DNA adducts formed from a range of lipid peroxidation products are …

… existence of specific endogenous DNA adducts of formaldehyde, VC… DNA adducts, amounts
of DNA adducts, and a short discussion of the mutagenic properties of various DNA adducts …

… interpretation of endogeDNA adducts exceed our ability to define the biological nous DNA
adducts. significance of … No clear role was identified by the Panel for endogenous or natural …

… At the same time I will take the opportunity to describe developments in the identification of
DNA adducts. A … This work has led to some understanding of the role of DNA adducts. Firstly, …

… to as DNA adducts (3-6) (Figure 1). Depending upon their structure, DNA adducts may (1)
block or significantly slow DNA … The presence of these enzymes in cells and their role in the …