过去一年中添加的文章,按日期排序

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK

M Korenjak, NA Temiz, SA Keita, B Chavanel… - bioRxiv, 2024 - biorxiv.org
5 天前 - … , while also investigating their role in human cancer. These … Next, we carried out
targeted DNA adduct analyses of … the formation of POB DNA adducts under the exposure …

Discovery of medicinal plant component for mycotoxin detoxification

MRK Kalemba - ujcontent.uj.ac.za
6 天前 - … Its carcinogenic potential has been attributed to the formation of DNA adducts and
… bioactive compounds with antioxidant activity playing a role in potent antifungal and/or AFB1 …

[HTML][HTML] Novel Techniques for Mapping DNA Damage and Repair in the Brain

J Hedlich-Dwyer, JS Allard, VE Mulgrave… - International Journal of …, 2024 - mdpi.com
7 天前 - … that aldehyde and acrolein DNA adducts occur in the neurodegenerative-diseased
brain, suggesting that our understanding of the role of exogenous and endogenous …

Strand-resolved mutagenicity of DNA damage and repair

Liver Cancer Evolution Consortium - Nature, 2024 - research.ed.ac.uk
22 天前 - … For small alkylation adducts of DNA, our results support a 42 model in … roles in
generating spatial 63 and temporal mutational asymmetries. The relative contribution of DNA

Sprtn Metalloprotease Participates in Repair of Ros-Mediated Dna-Protein Crosslinks

N Tretyakova, L Erber, AS Groehler, CI Cyuzuzo… - Available at SSRN … - papers.ssrn.com
33 天前 - … 0.1 adducts per 108 nucleotides were observed in the liver of unexposed mice. 9.7
± 13.2 and 38.7 ± 12.5 adducts per 108 nucleotides were observed in liver DNA … the roles of …

An Integrated LC-MS/MS Platform for Noninvasive Urinary Nucleus Acid Adductomics: A Pilot Study for Tobacco Exposure

X Li, H Zeng, L Zhang, J Zhang, Y Guo… - Journal of Hazardous …, 2024 - Elsevier
34 天前 - … levels in the tobacco smoke exposure group, highlighting the potential negative role
of … imbalances in nucleobase adducts like N 7 -methylguanine, DNA adducts such as N 6 -…

[引用][C] Developing a polymerase-driven method to incorporate base modifications & Structurally characterizing m6A-and colibactin-modified nucleic acids

R Haslecker - 2024

[PDF][PDF] Carcinogenicity of dietary MelQx in the prostate, breast, colon, and liver cancers, and the inhibitory effects of some compounds on MelQx: a mini review

TGB Silvaragi, A Seeni, M Nabil… - Food Research, 2024 - myfoodresearch.com
42 天前 - … the formation of DNA-carcinogen adducts, although some … equally plays a crucial
role in determining whether this … in breast tissues may form DNA adducts, which may result …

[PDF][PDF] IN VIVO MITOCHONDRIAL GENOTOXICITY OF DIETHYLSTILBESTROL: DIETHYLSTILBESTROL QUINONE IS ONE OF THE DNA BINDING METABOLITE (S) …

RD THOMAS, D ROY - The Role Of Mitochondrial Redox … - digitalcommons.library.uab.edu
43 天前 - adduct level was 3.85 x 10" 5 RAL and the total adduct level in the mtDNA was 1.98
x 10" 4 RAL. The ratio of mt DNA adducts to nDNA adducts … DES also formed DNA adducts

[HTML][HTML] Structural and mechanistic insights into the transport of aristolochic acids and their active metabolites by human serum albumin

S Pomyalov, CA Minetti, DP Remeta, R Bonala… - Journal of Biological …, 2024 - Elsevier
44 天前 - … In this study, we apply DNA adduct analysis, X-ray crystallography, isothermal
titration calorimetry, and fluorescence quenching to investigate the role of human serum albumin (…