Acetaldehyde as an underestimated risk factor for cancer development: role of genetics in ethanol metabolism
HK Seitz, F Stickel - Genes & nutrition, 2010 - Springer
… metabolic steps are modulated by the activity of the ethanol … Genes coding for these enzymes
harbor polymorphisms … In this review, the role of AA in carcinogenesis and genetic factors …
harbor polymorphisms … In this review, the role of AA in carcinogenesis and genetic factors …
[HTML][HTML] Genes encoding enzymes involved in ethanol metabolism
TD Hurley, HJ Edenberg - Alcohol research: current reviews, 2012 - ncbi.nlm.nih.gov
… the rate of ethanol’s processing (ie, metabolism) in the body. Ethanol can be metabolized in
… In humans, this primary pathway of ethanol metabolism involves oxidation to acetaldehyde …
… In humans, this primary pathway of ethanol metabolism involves oxidation to acetaldehyde …
Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism
E Quertemont - Molecular psychiatry, 2004 - nature.com
… role of acetaldehyde and ethanol metabolism in alcohol consumption and abuse. Ethanol
metabolism … Whereas alcohol dehydrogenase metabolizes the bulk of ethanol within the liver, …
metabolism … Whereas alcohol dehydrogenase metabolizes the bulk of ethanol within the liver, …
[HTML][HTML] The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants
HJ Edenberg - Alcohol Research & Health, 2007 - ncbi.nlm.nih.gov
… ethanol metabolism (Hurley et al. 2002). The main site of ethanol metabolism is the liver,
although some metabolism … The main pathway of ethanol metabolism involves its conversion (ie…
although some metabolism … The main pathway of ethanol metabolism involves its conversion (ie…
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Genetic and environmental factors affecting ethanol metabolism in man
ES Vesell, JG Page… - Clinical Pharmacology & …, 1971 - Wiley Online Library
… This study reveals that twofold variations in rates of ethanol metabolism among 14 pairs of …
genetic rather than environmental control. For 2 weeks before the tests of ethanol metabolism, …
genetic rather than environmental control. For 2 weeks before the tests of ethanol metabolism, …
Ethanol metabolism, toxicity and genetic polymorphism
K IWAHASHI, H SUWAKI - Addiction biology, 1998 - Wiley Online Library
… ethanol is whereas these symptoms have not been noted in metabolized by two non-ADH±ethanol …
the microsomal ethanol oxidizing other Mongoloid people show genetic polysystem (…
the microsomal ethanol oxidizing other Mongoloid people show genetic polysystem (…
Genetic factors in alcohol metabolism and alcoholism
WF Bosron, T Ehrig, TK Li - Seminars in liver disease, 1993 - thieme-connect.com
… metabolism. For this reason, the enzymatic pathways of ethanol metabolism and their control
by genetic … of ethanol oxidation in liver, and discusses the relationship of the discovered …
by genetic … of ethanol oxidation in liver, and discusses the relationship of the discovered …
Ethanol‐regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila
EC Kong, L Allouche, PA Chapot… - Alcoholism: Clinical …, 2010 - Wiley Online Library
… By using a combination of global gene expression analysis and a mutant survey, we
demonstrate that genes important for immunity, metabolism, olfaction, and protein acetylation …
demonstrate that genes important for immunity, metabolism, olfaction, and protein acetylation …
Genetic polymorphisms of alcohol metabolizing enzymes
DP Agarwal - Pathologie Biologie, 2001 - Elsevier
… The enzymatic pathways responsible for ethanol metabolism and their genetic as … and are
considered to play a major role in ethanol metabolism. The molecular characterization of ADH2…
considered to play a major role in ethanol metabolism. The molecular characterization of ADH2…
[HTML][HTML] Ethanol metabolism: The good, the bad, and the ugly
DF Wilson, FM Matschinsky - Medical hypotheses, 2020 - Elsevier
… We emphasize the role of energy metabolism and [AMP] f in … to ethanol but also their central
role in coordinating metabolic … just a metabolic disease, and there are substantial genetic, …
role in coordinating metabolic … just a metabolic disease, and there are substantial genetic, …