Acetaldehyde as an underestimated risk factor for cancer development: role of genetics in ethanol metabolism

HK Seitz, F Stickel - Genes & nutrition, 2010 - Springer
metabolic steps are modulated by the activity of the ethanolGenes coding for these enzymes
harbor polymorphisms … In this review, the role of AA in carcinogenesis and genetic factors …

[HTML][HTML] Genes encoding enzymes involved in ethanol metabolism

TD Hurley, HJ Edenberg - Alcohol research: current reviews, 2012 - ncbi.nlm.nih.gov
… the rate of ethanol’s processing (ie, metabolism) in the body. Ethanol can be metabolized in
… In humans, this primary pathway of ethanol metabolism involves oxidation to acetaldehyde …

Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism

E Quertemont - Molecular psychiatry, 2004 - nature.com
role of acetaldehyde and ethanol metabolism in alcohol consumption and abuse. Ethanol
metabolism … Whereas alcohol dehydrogenase metabolizes the bulk of ethanol within the liver, …

[HTML][HTML] The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants

HJ Edenberg - Alcohol Research & Health, 2007 - ncbi.nlm.nih.gov
ethanol metabolism (Hurley et al. 2002). The main site of ethanol metabolism is the liver,
although some metabolism … The main pathway of ethanol metabolism involves its conversion (ie…

Genetic and environmental factors affecting ethanol metabolism in man

ES Vesell, JG Page… - Clinical Pharmacology & …, 1971 - Wiley Online Library
… This study reveals that twofold variations in rates of ethanol metabolism among 14 pairs of …
genetic rather than environmental control. For 2 weeks before the tests of ethanol metabolism, …

Ethanol metabolism, toxicity and genetic polymorphism

K IWAHASHI, H SUWAKI - Addiction biology, 1998 - Wiley Online Library
ethanol is whereas these symptoms have not been noted in metabolized by two non-ADH±ethanol
the microsomal ethanol oxidizing other Mongoloid people show genetic polysystem (…

Genetic factors in alcohol metabolism and alcoholism

WF Bosron, T Ehrig, TK Li - Seminars in liver disease, 1993 - thieme-connect.com
metabolism. For this reason, the enzymatic pathways of ethanol metabolism and their control
by genetic … of ethanol oxidation in liver, and discusses the relationship of the discovered …

Ethanol‐regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila

EC Kong, L Allouche, PA Chapot… - Alcoholism: Clinical …, 2010 - Wiley Online Library
… By using a combination of global gene expression analysis and a mutant survey, we
demonstrate that genes important for immunity, metabolism, olfaction, and protein acetylation …

Genetic polymorphisms of alcohol metabolizing enzymes

DP Agarwal - Pathologie Biologie, 2001 - Elsevier
… The enzymatic pathways responsible for ethanol metabolism and their genetic as … and are
considered to play a major role in ethanol metabolism. The molecular characterization of ADH2…

[HTML][HTML] Ethanol metabolism: The good, the bad, and the ugly

DF Wilson, FM Matschinsky - Medical hypotheses, 2020 - Elsevier
… We emphasize the role of energy metabolism and [AMP] f in … to ethanol but also their central
role in coordinating metabolic … just a metabolic disease, and there are substantial genetic, …