[HTML][HTML] The role of imaging biomarkers to guide pharmacological interventions targeting tumor hypoxia
B Gallez - Frontiers in pharmacology, 2022 - frontiersin.org
Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
[HTML][HTML] Imaging biomarker roadmap for cancer studies
JPB O'connor, EO Aboagye, JE Adams… - Nature reviews Clinical …, 2017 - nature.com
… Imaging biomarkers must cross translational gap 1 to become robust medical research
tools, and translational gap 2 to be integrated into routine patient care. This goal is achieved …
tools, and translational gap 2 to be integrated into routine patient care. This goal is achieved …
Imaging biomarkers in prostate cancer: role of PET/CT and MRI
M Picchio, P Mapelli, V Panebianco… - … and molecular imaging, 2015 - Springer
… In the present review we evaluate the role of PET/CT and MRI findings as imaging biomarkers
of PCa, addressing their clinical impact on treatment management and prognosis in both …
of PCa, addressing their clinical impact on treatment management and prognosis in both …
[HTML][HTML] The role of imaging biomarkers in the assessment of sarcopenia
R Sanz-Requena, FM Martínez-Arnau… - Diagnostics, 2020 - mdpi.com
… The decrease of muscle quality precedes the loss of quantity, so we studied the role
magnetic resonance imaging biomarkers as indicators of the quantity and quality of muscle in …
magnetic resonance imaging biomarkers as indicators of the quantity and quality of muscle in …
Assessing the role of circulating, genetic, and imaging biomarkers in cardiovascular risk prediction
TJ Wang - Circulation, 2011 - Am Heart Assoc
… In summary, there are accumulating data on a variety of imaging biomarkers of cardiovascular
disease. Thus far, the strongest associations with events have been observed for coronary …
disease. Thus far, the strongest associations with events have been observed for coronary …
Using imaging biomarkers to accelerate drug development and clinical trials
HH Pien, AJ Fischman, JH Thrall, AG Sorensen - Drug discovery today, 2005 - Elsevier
… However, a range of new biomarkers, from imaging to genomics, have recently … of imaging
biomarkers set them apart from molecular, including genomic and proteomic, biomarkers. First…
biomarkers set them apart from molecular, including genomic and proteomic, biomarkers. First…
[HTML][HTML] The role of imaging biomarkers derived from advanced imaging and radiomics in the management of brain tumors
F Shaikh, D Dupont-Roettger, J Dehmeshki… - Frontiers in …, 2020 - frontiersin.org
… However, the role of imaging biomarkers … imaging biomarker for survival, independent of
MGMT promoter methylation (19). However, it is important to note that the role of this biomarker …
MGMT promoter methylation (19). However, it is important to note that the role of this biomarker …
Imaging biomarkers in oncology: basics and application to MRI
… In this review we will describe what constitutes an imaging biomarker, the principles of
imaging biomarker development, and the current status of imaging biomarkers with respect to MRI…
imaging biomarker development, and the current status of imaging biomarkers with respect to MRI…
[HTML][HTML] News about the role of fluid and imaging biomarkers in neurodegenerative diseases
J Meldolesi - Biomedicines, 2021 - mdpi.com
… imaging biomarkers presented in this section are profoundly different from the biomarkers of
… , they do not fit strictly the definition of biomarkers as distinct molecules related to pathology, …
… , they do not fit strictly the definition of biomarkers as distinct molecules related to pathology, …
Imaging biomarkers associated with cognitive decline: a review
J McConathy, YI Sheline - Biological psychiatry, 2015 - Elsevier
… are reliable biomarkers for detecting the … on imaging biomarkers. We highlight studies with
sufficient power to make meaningful conclusions concerning the role of imaging biomarkers in …
sufficient power to make meaningful conclusions concerning the role of imaging biomarkers in …