[HTML][HTML] The role of imaging biomarkers to guide pharmacological interventions targeting tumor hypoxia

B Gallez - Frontiers in pharmacology, 2022 - frontiersin.org
Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …

[HTML][HTML] Imaging biomarker roadmap for cancer studies

JPB O'connor, EO Aboagye, JE Adams… - Nature reviews Clinical …, 2017 - nature.com
Imaging biomarkers must cross translational gap 1 to become robust medical research
tools, and translational gap 2 to be integrated into routine patient care. This goal is achieved …

Imaging biomarkers in prostate cancer: role of PET/CT and MRI

M Picchio, P Mapelli, V Panebianco… - … and molecular imaging, 2015 - Springer
… In the present review we evaluate the role of PET/CT and MRI findings as imaging biomarkers
of PCa, addressing their clinical impact on treatment management and prognosis in both …

[HTML][HTML] The role of imaging biomarkers in the assessment of sarcopenia

R Sanz-Requena, FM Martínez-Arnau… - Diagnostics, 2020 - mdpi.com
… The decrease of muscle quality precedes the loss of quantity, so we studied the role
magnetic resonance imaging biomarkers as indicators of the quantity and quality of muscle in …

Assessing the role of circulating, genetic, and imaging biomarkers in cardiovascular risk prediction

TJ Wang - Circulation, 2011 - Am Heart Assoc
… In summary, there are accumulating data on a variety of imaging biomarkers of cardiovascular
disease. Thus far, the strongest associations with events have been observed for coronary …

Using imaging biomarkers to accelerate drug development and clinical trials

HH Pien, AJ Fischman, JH Thrall, AG Sorensen - Drug discovery today, 2005 - Elsevier
… However, a range of new biomarkers, from imaging to genomics, have recently … of imaging
biomarkers set them apart from molecular, including genomic and proteomic, biomarkers. First…

[HTML][HTML] The role of imaging biomarkers derived from advanced imaging and radiomics in the management of brain tumors

F Shaikh, D Dupont-Roettger, J Dehmeshki… - Frontiers in …, 2020 - frontiersin.org
… However, the role of imaging biomarkersimaging biomarker for survival, independent of
MGMT promoter methylation (19). However, it is important to note that the role of this biomarker

Imaging biomarkers in oncology: basics and application to MRI

I Dregely, D Prezzi, C Kelly‐Morland… - … Resonance Imaging, 2018 - Wiley Online Library
… In this review we will describe what constitutes an imaging biomarker, the principles of
imaging biomarker development, and the current status of imaging biomarkers with respect to MRI…

[HTML][HTML] News about the role of fluid and imaging biomarkers in neurodegenerative diseases

J Meldolesi - Biomedicines, 2021 - mdpi.com
imaging biomarkers presented in this section are profoundly different from the biomarkers of
… , they do not fit strictly the definition of biomarkers as distinct molecules related to pathology, …

Imaging biomarkers associated with cognitive decline: a review

J McConathy, YI Sheline - Biological psychiatry, 2015 - Elsevier
… are reliable biomarkers for detecting the … on imaging biomarkers. We highlight studies with
sufficient power to make meaningful conclusions concerning the role of imaging biomarkers in …