[HTML][HTML] p38 MAP-kinases pathway regulation, function and role in human diseases

A Cuenda, S Rousseau - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
… Similar roles in the activation of the p38 MAPK pathway have also been proposed for the
members of the JNK-interacting protein (JIP) family JIP2 and JIP4, which are scaffold proteins …

Role of p38 MAP kinase signal transduction in solid tumors

HK Koul, M Pal, S Koul - Genes & cancer, 2013 - journals.sagepub.com
… the clinical significance of p38 MAPK signaling pathways. … p38 MAPK pathways with respect
to solid tumor biology and generate testable hypothesis with respect to the role of p38 MAPK

Mechanisms and functions of p38 MAPK signalling

A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
… to the availability of inhibitors for the several MAPK families that usually function as parallel
… the p38 MAPK pathway, which is strongly activated by stress, but also plays important roles in …

p38 MAPK signalling cascades: ancient roles and new functions

E Martín‐Blanco - Bioessays, 2000 - Wiley Online Library
… and developmental roles of this subfamily of MAPKs in light to the recent identification … p38
homologues in Drosophila. The p38 MAPKs p38 was first identified in 1994 as a MAP kinase

The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease

SAL Corrêa, KL Eales - Journal of signal transduction, 2012 - Wiley Online Library
… an overview of p38 MAPK localisation, activation, and the functional role of this signalling …
of the p38 MAPK cascade during synaptic plasticity in the hippocampus. Although p38 MAPK

The role of p38 MAPK in the development of diabetic cardiomyopathy

S Wang, L Ding, H Ji, Z Xu, Q Liu, Y Zheng - International journal of …, 2016 - mdpi.com
… the current literature base to provide an overview of the roles of p38 MAPK in DCM. … role of
p38 MAPK in dendritic cell function [37]. ROS can activate p38 MAPK; and, in turn, p38 MAPK

Critical role of p38 MAPK in IL‐4‐induced alternative activation of peritoneal macrophages

L Jiménez‐Garcia, S Herránz, A Luque… - European Journal of …, 2015 - Wiley Online Library
role in macrophages is still controversial. In this study, we investigated whether p38 MAPK
plays a role … Our results reveal that IL-4 induces phosphorylation of p38 MAPK in thioglycollate…

Role of p38 MAPK in atherosclerosis and aortic valve sclerosis

A Reustle, M Torzewski - International journal of molecular sciences, 2018 - mdpi.com
… active, inflammation-driven processes, the p38 MAPK has gained attention in this research
field. An increasing number of studies investigating p38 MAPK signaling in different cell types …

Roles of p38 MAPKs in invasion and metastasis

I del Barco Barrantes… - Biochemical Society …, 2012 - portlandpress.com
… can potentially perform overlapping roles with p38α, whereas … p38 MAPKs in tumour
development have been reviewed in [6,7]. In the present paper, we focus on the roles of p38 MAPKs

Role of p38 MAP kinase in myocardial stress

DS Nagarkatti, IS Ramadan - Journal of molecular and cellular …, 1998 - Elsevier
The current study focuses on the role of p38 MAP kinase in response to acute preconditioning
stimuli and ischemia. Exposure of the rat myoblast cell line H9C2 to preconditioning stimuli…