Role of tachykinin NK1, NK2 and NK3 receptors in the modulation of visceral hypersensitivity in the rat

GA Gaudreau, V Plourde - Neuroscience letters, 2003 - Elsevier
Tachykinins are known to be involved in the processing of … of tachykinin receptor antagonists
in the mediation of visceral hypersensitivity. Intrathecal administration of the NK 1 receptor

The tachykinin NK1 receptor in the brain: pharmacology and putative functions

A Saria - European journal of pharmacology, 1999 - Elsevier
… NK 3 receptor, respectively. The present review focuses on the … function of tachykinin NK
1 receptors in brain. The natural ligand with the highest affinity for the tachykinin NK 1 receptor

The study of tachykinin receptors

E Burcher - Clinical and experimental pharmacology and …, 1989 - Wiley Online Library
NK2 receptors are found on gastrointestinal and urinary smooth muscle, but few peripheral
functions of NKB has been hindered by lack of specific antibodies and selective radioligands. …

Tachykinins and tachykinin receptors in the gut, with special reference to NK2 receptors in human

A Lecci, A Capriati, M Altamura, CA Maggi - Autonomic Neuroscience, 2006 - Elsevier
… TKs and in the role of their receptors, the selective blockade of tachykinin NK2 receptors can
have … and perception, but this can occur without the disruption of the physiological functions. …

Role of tachykinin NK1 and NK2 receptors in allergen‐induced early and late asthmatic reactions, airway hyperresponsiveness, and airway inflammation in …

M Schuiling, AB Zuidhof, J Zaagsma… - Clinical & Experimental …, 1999 - Wiley Online Library
… selective nonpeptide tachykinin NK1 and NK2 receptor antagonists … the NK2 receptor
antagonist SR 48968, but not the NK1 receptor … Both NK receptor antagonists tended to reduce the …

Tachykinin NK2 receptor antagonists for the treatment of irritable bowel syndrome

A Lecci, A Capriati, CA Maggi - British journal of pharmacology, 2004 - Wiley Online Library
Tachykinin NK2 receptors are expressed in the gastrointestinal … Experimental data indicate
a role for these receptors in the … importance of NK2 receptors predominates over that of NK1

Blockade of Tachykinin NK1/NK2 Receptors in the Brain Attenuates the Activation of Corticotrophin‐Releasing Hormone Neurones in the Hypothalamic …

J Culman, G Das, C Ohlendorf, M Haass… - Journal of …, 2010 - Wiley Online Library
… The design of our experiments does not allow the definition of the putative role of each
tachykinin receptor in the regulation of catecholamine release in response to formalin-induced …

Role of tachykinin NK1 and NK2 receptors on colonic motility in anesthetized rats: effect of agonists

A Lecci, M Tramontana, S Giuliani… - Canadian journal of …, 1997 - cdnsciencepub.com
… effects of selective NK1 and NK2 receptor agonists, and … function of NK1 and NK2 receptors
could be differentiated in terms of colonic motility and to characterize a novel NK2 receptor

Role of tachykinin NK1 and NK2 receptors in colonic sensitivity and stress-induced defecation in gerbils

D Kakol-Palm, M Brusberg, E Sand, H Larsson… - European journal of …, 2008 - Elsevier
… The tachykinin NK receptors have previously been implicated in … , we examined the role of
tachykinin NK 1 and NK 2 receptors in … , a species with human-like NK receptor pharmacology. …

Characterization of NK1 and NK2 tachykinin receptors in guinea‐pig and rat bronchopulmonary and vascular systems

A Floch, V Fardin, I Cavero - British journal of pharmacology, 1994 - Wiley Online Library
… distribution and function of the different tachykinin receptors at the … and lungs were performed
and tachykinin receptor-mediated … agonists and antagonists of NK, and NK2 receptors. …