Androgen receptor: an overview

C Chang, A Saltzman, S Yeh, W Young… - Critical Reviews™ in …, 1995 - dl.begellhouse.com
… ABSTRACT: The action of androgens in regulating development and growth … androgen
receptor (AR). AR is a member of the steroid hormone receptor superfamily, a class of receptors

Revising the role of the androgen receptor in breast cancer

FM Fioretti, A Sita-Lumsden… - Journal of molecular …, 2014 - jme.bioscientifica.com
… Potential mechanisms of crosstalk between the androgen receptor and oestrogen receptor
α pathways. (1) In classical ERα signalling, the ligand-bound receptor binds to specific DNA …

Role of the androgen receptor in human breast cancer

SN Birrell, RE Hall, WD Tilley - Journal of mammary gland biology and …, 1998 - Springer
… Although the androgen receptor (AR) 3 is often co-expressed with the estrogen receptor (ER)and
progesterone receptor (PR) in human breast tumors,its role in breast cancer is poorly …

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

DR Cochrane, S Bernales, BM Jacobsen… - Breast Cancer …, 2014 - Springer
… The androgen receptor (AR) is widely expressed in breast cancers and has … receptor alpha
(ER) negative breast cancers that retain AR. However, controversy exists regarding the role of …

Androgen receptor: structure, role in prostate cancer and drug discovery

MH Tan, J Li, HE Xu, K Melcher, E Yong - Acta Pharmacologica Sinica, 2015 - nature.com
Androgens and androgen receptors (AR) play a pivotal role in expression of the male
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate cancer, …

Triple-negative breast cancer: role of the androgen receptor

A Gucalp, TA Traina - The Cancer Journal, 2010 - journals.lww.com
… The androgen receptor (AR), a member of the steroid hormone receptor family, is expressed
in … The role of the AR is of particular interest in patients with estrogen-and progesterone …

Drug insight: role of the androgen receptor in the development and progression of prostate cancer

ME Taplin - Nature Clinical Practice Oncology, 2007 - nature.com
… Functional androgen receptor (AR) signaling is necessary for the development of prostate
cancer. The therapeutic effect of androgen deprivation therapy for prostate cancer was …

[HTML][HTML] Role of the androgen receptor in triple-negative breast cancer

M Rampurwala, KB Wisinski… - Clinical advances in …, 2016 - ncbi.nlm.nih.gov
role of androgen signaling in a subset of TNBC is emerging. Although the degree of androgen
receptor (… has been used to identify a luminal androgen receptor subtype of TNBC that is …

The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancer

B Chatterjee - Molecular and cellular biochemistry, 2003 - Springer
The androgen receptor (AR) is an androgen-inducible transcription factor characterized by a
modular primary structure, with each module representing a distinct functional unit. After its …

The role of androgens and the androgen receptor in prostate cancer

JD Debes, DJ Tindall - Cancer letters, 2002 - Elsevier
… However, most tumors will eventually relapse in an androgen-refractory state. This review
will address the role of androgens and other factors in the development and progression of …