Roles for Ca2+ and K+ channels in cancer cells exposed to the hypoxic tumour microenvironment

A Girault, A Ahidouch, H Ouadid-Ahidouch - Biochimica et Biophysica Acta …, 2020 - Elsevier
… The focus of our review is the role of Ca 2+ and K + channels in the relation between
hypoxia tumour condition and cancer cell responses. Nevertheless, other studies report the …

Role of the tumor microenvironment in breast cancer

SD Soysal, A Tzankov, SE Muenst - Pathobiology, 2015 - karger.com
cancer microenvironment, the alterations in molecular signatures of cells comprising this
microenvironment, their interplay with cancer … PD-L1 with antibodies capable of inhibiting this …

Tumor microenvironment

B Arneth - Medicina, 2019 - mdpi.com
… cells in the tumor microenvironment play critical roles in all the … the concept of the tumor
microenvironment by conducting a … a key role in tumor development and tumor cell protection …

The tumor microenvironment

NM Anderson, MC Simon - Current Biology, 2020 - cell.com
role of immune cells in the tumor microenvironment can be to either suppress tumor formation
(anti-tumor microenvironment… -suppressive microenvironment). Depending on context and …

[HTML][HTML] Role of tumor microenvironment in tumorigenesis

M Wang, J Zhao, L Zhang, F Wei, Y Lian, Y Wu… - … of Cancer, 2017 - ncbi.nlm.nih.gov
tumor microenvironment and characteristics of cancer. It is currently widely recognized that
tumor microenvironments are wildly influenced by the ten main characteristics of cancer: A. …

The hypoxic tumour microenvironment

V Petrova, M Annicchiarico-Petruzzelli, G Melino… - Oncogenesis, 2018 - nature.com
… of the tumour microenvironment, and we summarise their role in cancer development and
… and extracellular Ca2+-binding protein S100A4 with subsequent tumour progression and …

LncRNA CamK-A regulates Ca2+-signaling-mediated tumor microenvironment remodeling

L Sang, H Ju, G Liu, T Tian, G Ma, Y Lu, Z Liu, R Pan… - Molecular cell, 2018 - cell.com
… human cancers and involved in cancer microenvironment remodeling via activation of Ca 2+
-… We next use this chemically inducible system to investigate the role of CaMK kinase PNCK …

Tumor microenvironment: the role of the tumor stroma in cancer

H Li, X Fan, JM Houghton - Journal of cellular biochemistry, 2007 - Wiley Online Library
tumor microenvironment, composed of non-cancer cells and their stroma, has become
recognized as a major factor influencing the growth of cancer… specific cancer microenvironments. …

Evolving roles of CD38 metabolism in solid tumour microenvironment

L Gao, X Du, J Li, FXF Qin - British Journal of Cancer, 2023 - nature.com
… metabolism of ADPR/cADPR in the tumour microenvironment are due to both ADPR and
cADPR being dynamic second messengers for manipulating the influx of Ca 2+ , a very complex…

Multifunctional Calcium–Manganese Nanomodulator Provides Antitumor Treatment and Improved Immunotherapy via Reprogramming of the Tumor Microenvironment

G Luo, X Li, J Lin, G Ge, J Fang, W Song, GG Xiao… - ACS …, 2023 - ACS Publications
… a cancer cell membrane. This nanoplatform was aimed at reprogramming the tumor
microenvironment … Inspired by the biological functions of Ca 2+ and Mn 2+ , we hypothesized that …