Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells

J Wang, B Luo, X Li, W Lu, J Yang, Y Hu, P Huang… - Cell death & …, 2017 - nature.com
… First, we tested ROS level alteration in lung and colorectal cancer cell lines after drug …
After 6-h treatment, 10 μM LBL21 induced tremendous accumulation of ROS relative to PEITC, …

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

R Zhang, I Humphreys, RP Sahu, Y Shi, SK Srivastava - Apoptosis, 2008 - Springer
… human pancreatic cancer cells is initiated by the generation of ROS, … We next wanted to see
whether ROS generation is an … pretreatment not only blocks ROS generation but also offers …

Corilagin induces apoptosis, autophagy and ROS generation in gastric cancer cells in vitro

J Xu, G Zhang, Y Tong, J Yuan… - … journal of molecular …, 2019 - spandidos-publications.com
… , but are also efficient therapeutic tools in treating cancer (29). In the present study, intracellular
ROS production was detected using a DCFH-DA probe in gastric cancer cells. Following …

G226, a new epipolythiodioxopiperazine derivative, triggers DNA damage and apoptosis in human cancer cells in vitro via ROS generation

P He, J Zhang, Y Che, Q He, Y Chen… - Acta Pharmacologica …, 2014 - nature.com
tumor cells 28 . In this study, we verified that G226 could quickly induce ROS generation in
cancer cells… , all effectively decreased G226-induced ROS enhancement and the subsequent …

Oxidative Stress Modulation and ROS‐Mediated Toxicity in Cancer: A Review on In Vitro Models for Plant‐Derived Compounds

MJ Vallejo, L Salazar, M Grijalva - … Medicine and Cellular …, 2017 - Wiley Online Library
… is made on cancer cell models. In the next sections, an overview of in vitro assessment of …
antioxidant and oxidative stress-modulating properties in cancer cell lines is presented. …

Enhancement of cisplatin-induced colon cancer cells apoptosis by shikonin, a natural inducer of ROS in vitro and in vivo

G He, G He, R Zhou, Z Pi, T Zhu, L Jiang… - … and biophysical research …, 2016 - Elsevier
… colon cancer cell apoptosis through generation of ROS. … induced human colon cancer cell
killing in vitro and in vivo. The … critical role of ROS in combined treatment-induced cell death. …

Usnic acid induces apoptosis via an ROS-dependent mitochondrial pathway in human breast cancer cells in vitro and in vivo

S Zuo, L Wang, Y Zhang, D Zhao, Q Li, D Shao… - RSC Advances, 2015 - pubs.rsc.org
… Based on these, the cytotoxic activity of UA toward human breast cancer cells and the …
of human breast cancer MCF-7 cells through the following processes: ROS generation, JNK …

ROS-modulated therapeutic approaches in cancer treatment

MH Raza, S Siraj, A Arshad, U Waheed… - Journal of cancer …, 2017 - Springer
… of ROS and cancer cells, different ROS-mediated therapeutic strategies and the emerging role
of microbiota in cancer … promising results in vitro as well as in vivo. In addition, response to …

[HTML][HTML] … potential of Conium maculatum extract against cancer cells in vitro: Drug-DNA interaction and its ability to induce apoptosis through ROS generation

J Mondal, AK Panigrahi… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
… been carried out to test its anti-cancer potential against cervix cancer cells in vitro. Thus, in
this study, … in different normal and cancer cell lines including an elaborate study in HeLa cells. …

Jungermannenone A and B induce ROS-and cell cycle-dependent apoptosis in prostate cancer cells in vitro

Y Guo, Z Lin, M Wang, Y Dong, H Niu… - Acta Pharmacologica …, 2016 - nature.com
… show anti-proliferation activities in cancer cells. In this study we investigated the mechanisms
underlying the anticancer action of JA and JB in PC3 human prostate cancer cells in vitro. …