ROS stress in cancer cells and therapeutic implications
H Pelicano, D Carney, P Huang - Drug resistance updates, 2004 - Elsevier
… Despite the negative impacts of increased ROS in cancer cells, it is possible to exploit …
cancer cells through ROS-mediated mechanisms. This article reviews ROS stress in cancer cells, …
cancer cells through ROS-mediated mechanisms. This article reviews ROS stress in cancer cells, …
[HTML][HTML] ROS homeostasis and metabolism: a dangerous liason in cancer cells
E Panieri, MM Santoro - Cell death & disease, 2016 - nature.com
… by sustained ROS production, cancer cells have developed an efficient mechanism of ROS
… Therefore, the dependency of cancer cells from their antioxidant systems represents a …
… Therefore, the dependency of cancer cells from their antioxidant systems represents a …
Production and detection of reactive oxygen species (ROS) in cancers
D Wu, P Yotnda - JoVE (Journal of Visualized Experiments), 2011 - jove.com
… Detection of protein oxidation investigates the total effects of all ROS produced by the
studied cells; here the intensity of the signal obtained represents the amount of ROS produced. …
studied cells; here the intensity of the signal obtained represents the amount of ROS produced. …
Reactive oxygen species (ROS): key components in cancer therapies
… of ROS involved in different pathways of killing cancer cells during the development of
anti-cancer … pathway of ROS in cancer cells and the identification of specific ROS targets that can …
anti-cancer … pathway of ROS in cancer cells and the identification of specific ROS targets that can …
Cancer cell killing via ROS: to increase or decrease, that is the question
J Wang, J Yi - Cancer biology & therapy, 2008 - Taylor & Francis
… therapeutic approaches for cancers, including … cell death, therefore ROS are also used to
kill cancer cells. Because of the double-edged sword property of ROS in determining cell fate, …
kill cancer cells. Because of the double-edged sword property of ROS in determining cell fate, …
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
D Trachootham, J Alexandre, P Huang - Nature reviews Drug discovery, 2009 - nature.com
… An increase in ROS is associated with abnormal cancer cell … elevation of ROS production
or to a decline of ROS-scavenging … Because the increase of ROS in cancer cells may play an …
or to a decline of ROS-scavenging … Because the increase of ROS in cancer cells may play an …
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
IR Indran, MP Hande, S Pervaiz - Cancer research, 2011 - AACR
… not only reduces the basal cellular reactive oxygen species (ROS) levels but also inhibits
endogenous ROS production in response to stimuli that induce intracellular ROS generation. …
endogenous ROS production in response to stimuli that induce intracellular ROS generation. …
[HTML][HTML] Reactive oxygen species in cancer cells: live by the sword, die by the sword
PT Schumacker - Cancer cell, 2006 - cell.com
… in cancer cells is often viewed as an adverse event. Here, we show that such abnormal
increases in ROS can be exploited to selectively kill cancer cells … of ovarian epithelial cells with H-…
increases in ROS can be exploited to selectively kill cancer cells … of ovarian epithelial cells with H-…
[HTML][HTML] Understanding the mechanism of action of melatonin, which induces ROS production in cancer cells
J Florido, C Rodriguez-Santana, L Martinez-Ruiz… - Antioxidants, 2022 - mdpi.com
… This review described the possible pathways involved in ROS production by melatonin in
cancer cells. These mechanisms include, besides melatonin receptors, sirtuins and Akt …
cancer cells. These mechanisms include, besides melatonin receptors, sirtuins and Akt …
ROS and energy metabolism in cancer cells: alliance for fast growth
SW Kang, S Lee, EK Lee - Archives of pharmacal research, 2015 - Springer
… , we review the complex connection between ROS and energy metabolisms in cancer cells.
… analyses of cancer cell-specific metabolism along with the ROS production and elimination …
… analyses of cancer cell-specific metabolism along with the ROS production and elimination …
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