Chemopreventive effects of rosmarinic acid on rat colon carcinogenesis
RA Furtado, BR Oliveira, LR Silva… - … Journal of Cancer …, 2015 - journals.lww.com
… lead to colon cancer. Rat and human ACF show defects in DNA content, morphology, and
proliferation kinetics, and mutations have been detected in key genes involved in colon cancer …
proliferation kinetics, and mutations have been detected in key genes involved in colon cancer …
Biochemical and molecular mechanisms underlying the chemopreventive efficacy of rosmarinic acid in a rat colon cancer
K Venkatachalam, S Gunasekaran… - European Journal of …, 2016 - Elsevier
… colon carcinogenesis in rats. The increased incidence of aberrant crypts in the DMH exposed
rats … ) decrease of weight gain and growth rate in carcinogen exposed rats (groups 3–6), it …
rats … ) decrease of weight gain and growth rate in carcinogen exposed rats (groups 3–6), it …
The effect of rosmarinic acid on 1, 2-dimethylhydrazine induced colon carcinogenesis
K Venkatachalam, S Gunasekaran… - Experimental and …, 2013 - Elsevier
… This study was carried out to investigate the chemopreventive potential of rosmarinic acid
(RA) against 1,2-dimethylhydrazine (DMH) induced rat colon carcinogenesis by evaluating the …
(RA) against 1,2-dimethylhydrazine (DMH) induced rat colon carcinogenesis by evaluating the …
Modulatory efficacy of rosmarinic acid on premalignant lesions and antioxidant status in 1, 2-dimethylhydrazine induced rat colon carcinogenesis
V Karthikkumar, G Sivagami, R Vinothkumar… - Environmental …, 2012 - Elsevier
… Rosmarinic acid (RA), one of the major components of polyphenol possesses attractive …
) induced rat colon carcinogenesis by evaluating the circulatory antioxidant status and colonic …
) induced rat colon carcinogenesis by evaluating the circulatory antioxidant status and colonic …
Rosmarinic acid inhibits DMH-induced cell proliferation in experimental rats
V Karthikkumar, G Sivagami… - Journal of basic and …, 2015 - degruyter.com
… effects of rosmarinic acid (RA) in 1,2-dimethylhydrazine (DMH)-induced rat colon carcinogenesis.
… of DMH induces multiple tumors in the rat colon, which mimics human colon cancer. …
… of DMH induces multiple tumors in the rat colon, which mimics human colon cancer. …
Protective effects of rosmarinic acid against azoxymethane‐induced colorectal cancer in rats
N Ilhan, I Bektas, S Susam… - Journal of Biochemical …, 2022 - Wiley Online Library
… )-induced rat colon carcinogenesis by evaluating … Rats were fed a modified pellet diet (15.8%
peanut oil was added to the standard diet) during the experimental period. Colon cancer …
peanut oil was added to the standard diet) during the experimental period. Colon cancer …
[PDF][PDF] Promising therapeutic role of Rosmarinus officinalis successive methanolic fraction against colorectal cancer
… The chemopreventive effect of rosmarinic acid on colon carcinogenesis is evidenced by the
decreased incidence and distribution of tumors along the colon. This effect of rosmarinic acid …
decreased incidence and distribution of tumors along the colon. This effect of rosmarinic acid …
Therapeutic potential of rosmarinic acid: A comprehensive review
… RA application, at a concentration of 5 mg/kg bw during 30 weeks in 1,2-dimethyldrazin
stimulated colon carcinogenesis in the rat at 20 mg/kg bw and significantly stopped tumor …
stimulated colon carcinogenesis in the rat at 20 mg/kg bw and significantly stopped tumor …
Rosmarinic acid and related dietary supplements: Potential applications in the prevention and treatment of cancer
J Zhao, L Xu, D Jin, Y Xin, L Tian, T Wang, D Zhao… - Biomolecules, 2022 - mdpi.com
… These extracts inhibited proliferation in breast cancer and colon cancer cell lines via the
mitogen-activated protein kinase (MAPK)/ extracellular signal-regulated kinases 1 and 2 (ERK1/…
mitogen-activated protein kinase (MAPK)/ extracellular signal-regulated kinases 1 and 2 (ERK1/…
[HTML][HTML] Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis
BR Jin, KS Chung, S Hwang, SN Hwang, KJ Rhee… - Neoplasia, 2021 - Elsevier
… on colon cancer induction and found that inflammatory microenvironments could advance
colon cancer via … Enhanced TLR4 activation was confirmed in colon cancer patients with long-…
colon cancer via … Enhanced TLR4 activation was confirmed in colon cancer patients with long-…
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