Biphasic modulation of spinal visceral nociceptive transmission from the rostroventral medial medulla in the rat

M Zhuo, JN Sengupta… - Journal of …, 2002 - journals.physiology.org
… 15 Fields HL, Basbaum AICentral nervous system mechanisms of pain modulation.Textbook
of Pain4th ed., Wall PD, Melzack R1999309329Churchill-LivingstoneNew York …

Facilitation and attenuation of a visceral nociceptive reflex from the rostroventral medulla in the rat

M Zhuo, GF Gebhart - Gastroenterology, 2002 - Elsevier
… descending modulation from the rostroventral medulla (RVM). … reflexes are subject to
facilitatory modulation from the RVM, … increased pain in the presence of modest input or even pain

Pain modulation from the brain during diabetic neuropathy: uncovering the role of the rostroventromedial medulla

M Silva, JT Costa-Pereira, D Martins, I Tavares - Neurobiology of disease, 2016 - Elsevier
rostroventromedial medulla (RVM) is a key pain control center involved in descending pain
modulation … mechanisms that mediate nociceptive modulation from the RVM during diabetes …

Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation

ST Lubejko, G Livrizzi, SA Buczynski, J Patel… - Science …, 2024 - science.org
… the rostroventromedial medulla (RVM), the suppression of which disinhibits LC neurons to
drive spinal noradrenergic antinociception. We describe pain-… of descending pain modulation. …

Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain

M De Felice, R Sanoja, R Wang, L Vera-Portocarrero… - Pain, 2011 - journals.lww.com
… ventromedial medulla (RVM), a site that integrates descending pain modulation via pain
Our data demonstrate that descending modulation from the RVM reduces the impact of pain

Descending pain modulation and chronification of pain

MH Ossipov, K Morimura, F Porreca - Current opinion in …, 2014 - journals.lww.com
… The PAG influences descending pain modulation primarily through its reciprocal connections
with the rostroventromedial medulla (RVM) [57] . For example, excitation of PAG neurons …

Noradrenergic pain modulation

A Pertovaara - Progress in neurobiology, 2006 - Elsevier
… the duration of the pain and pathophysiological condition. … pain induces noradrenergic
feedback inhibition of pain. Noradrenergic systems may also contribute to top-down control of pain

[HTML][HTML] A critical period in the supraspinal control of pain: opioid-dependent changes in brainstem rostroventral medulla function in preadolescence

GJ Hathway, D Vega-Avelaira, M Fitzgerald - PAIN®, 2012 - Elsevier
… This supraspinal pain modulation is mediated by networks distributed throughout the limbic
… ventral medulla (RVM) [4], [5], [6], [10]. The importance of endogenous pain modulation via …

Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy

M Silva, D Martins, A Charrua, F Piscitelli, I Tavares… - …, 2016 - Elsevier
… In order to study the role of endovanilloid signalling in RVM-mediated pain modulation in
an experimental model of DNP, we evaluated the local expression of TRPV1 and FAAH and …

Rostroventral medulla-mediated biphasic modulation of the rat cardiosomatic motor reflex

N Sun, XH Liu, JQ Du, JX Zhu, JS Tang, Q Li - Neuroscience, 2011 - Elsevier
… the rostroventral portion of the medulla oblongata (RVM) exerts descending modulation on
the … Whether cardiac pain is modulated biphasically has not previously been shown, although …