Using a model of visceral nociception, we examined whether cholecystokinin (CCK) acts as
an anti-opioid peptide in the rat rostral ventromedial medulla (RVM). Because such …

… Interestingly, a drop in electrical pain threshold of 200 µA, as … that the strength of descending
modulation was not correlated to the … modulation of dorsal horn circuits is tuned to modulate …

… rostral ventromedial medulla (RVM) in neuropathic pain, but … a model of neuropathic pain
that produces robust mechanical … of neutral cells in pain modulation remains an open question. …

… pain partly results from central changes caused by alterations in neurons in the rostral
ventromedial medulla (… The output of descending pain-modulating pathway can be influenced by …

… pain-modulating systems, the best characterized of which is the rostral ventromedial medulla
… direct, functionally relevant inputs to RVM pain-modulating neurons from PB. Whole-cell …

… possesses networks that modulate the processing of nociceptive information. One network,
with critical links in the midbrain periaqueductal gray and rostral ventromedial medulla (RVM)…

… pain modulation arising from the periaqueductal gray (PAG) and activating the rostral
ventromedial medulla (RVM) and noradrenergic nuclei to block ascending nociceptive inputs. …

… RF in pain transmission and modulation in animal models of pain, in this article we critically
review the participation of the medullary RF in pain modulation. The medulla oblongata …

… to modulate spinal processing of sensory input in a top-down fashion. The rostral ventromedial
medulla (… We examined RVM activity associated with experimental neuropathic pain, but …

… Substantial evidence supports the concept that descending pain modulatory systems from
the medulla play an important role in the expression of injury-induced behaviors. Numerous …