[引用][C] Descending modulation of pain

MH Ossipov, F Porreca - The paths of pain, 1975 - Springer

Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions

R Staud - Expert review of neurotherapeutics, 2012 - Taylor & Francis
… inhibition depends on activation of the prefrontal cortex, periaqueductal gray and rostral
ventral medulla. Quantitative sensory test paradigms have been designed to acquire detailed …

[HTML][HTML] Physiological properties of pain-modulating neurons in rostral ventromedial medulla in female rats, and responses to opioid administration

G Hryciw, CC De Preter, J Wong, MM Heinricher - Neurobiology of Pain, 2021 - Elsevier
pain-modulation circuits, the physiology of pain-modulating neurons that comprise a major
functional output, the rostral ventromedial medulla … and characterize pain-modulating neurons …

Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity

J Roberts, MH Ossipov… - European Journal of …, 2009 - Wiley Online Library
… The data show that inflammatory pain is associated with glial activation in the RVM that …
pain facilitation. These findings reveal a novel site of glial modulation of inflammatory pain. …

[HTML][HTML] Altered brainstem pain modulating circuitry functional connectivity in chronic painful temporomandibular disorder

EP Mills, R Akhter, F Di Pietro, GM Murray, CC Peck… - … Journal of Pain, 2021 - Elsevier
… Given their similar neurochemical and modulatory properties, some have suggested that
the RVM and SRD are components of a pain-modulation triad within the medulla that together …

Altered brainstem pain-modulation circuitry connectivity during spontaneous pain intensity fluctuations

EP Mills, Z Alshelh, D Kosanovic, F Di Pietro… - Journal of Pain …, 2020 - Taylor & Francis
… To study the function of the brainstem pain-modulation system, we performed functional …
rostral ventromedial medulla (RVM). The RVM is in the center of several pain-modulation circuits …

Effects of vagal afferent stimulation on ON and OFF cells in the rostroventral medulla: relationships to nociception and arterial blood pressure

CL Thurston, A Randich - Journal of neurophysiology, 1992 - journals.physiology.org
… of 125 neurons in the rostroventral medulla (RVM) were … the modulation of nociception in the
manner previously proposed. … pain modulating neurons in the rostra1 ventral medulla: reflex…

[HTML][HTML] Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs

LFS da Silva, MR Coutinho… - Brain research bulletin, 2010 - Elsevier
… in the RVM on an affective-motivational pain model. Additionally, we … pain control system;
indicating an interaction between the opioidergic and GABAergic pathways of pain modulation

Bulbospinal projections in the primate: a light and electron microscopic study of a pain modulating system

AI Basbaum, DD Ralston… - Journal of Comparative …, 1986 - Wiley Online Library
… the rostroventral medulla with 3H-leucine and examination of the resultant labeled axons
and terminals by light and electron microscopic autoradiography. Five monkeys had accurately …

Anatomy of trigeminal neuromodulation targets: from periphery to the brain

E Goellner, CE Rocha - Neuromodulation for Facial Pain, 2020 - karger.com
… In another pathway, the PBN neurons also connect directly to the rostral ventrolateral
medulla, which is an important part of the descending pain modulation system together with …