Pain modulation from the brain during diabetic neuropathy: uncovering the role of the rostroventromedial medulla

M Silva, JT Costa-Pereira, D Martins, I Tavares - Neurobiology of disease, 2016 - Elsevier
… in type 1 diabetes. Given the paramount role of the rostroventromedial medulla (RVM) in …
focus in this key area of the pain modulatory system in an animal model of type 1 diabetes. …

Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy

M Silva, D Martins, A Charrua, F Piscitelli, I Tavares… - …, 2016 - Elsevier
… during the installation of diabetic neuropathy. … that the installation of diabetic neuropathy
triggers the expression of … shift of TRPV1 expression during diabetic neuropathy. In fact, in …

Pronociceptive changes in the activity of rostroventromedial medulla (RVM) pain modulatory cells in the streptozotocin-diabetic rat

M Silva, D Amorim, A Almeida, I Tavares… - Brain research …, 2013 - Elsevier
rostroventromedial medulla (RVM), a key brainstem area involved in descending modulation
of nociceptive neurotransmission at the spinal cord, in STZ-diabetic … of diabetic neuropathy

Pronociceptive changes in response properties of rostroventromedial medullary neurons in a rat model of peripheral neuropathy

L Gonçalves, A Almeida… - European Journal of …, 2007 - Wiley Online Library
… The spared nerve injury (SNI) model of peripheral neuropathy produces a robust and long-…
through the rostroventromedial medulla (RVM) contribute to neuropathic hypersensitivity. We …

Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats

A Pertovaara, H Wei, MM Hämäläinen - Neuroscience letters, 1996 - Elsevier
… In the present study we attempted to find out if the rostroventromedial medulla (RVM) or
the periaqueductal gray (PAG) might contribute to chronic allodynia induced by unilateral …

The rostroventromedial medulla is engaged in the effects of spinal cord stimulation in a rodent model of neuropathic pain

Z Song, OB Ansah, BA Meyerson, A Pertovaara… - Neuroscience, 2013 - Elsevier
… The neurobiological mechanisms underlying the suppression of neuropathic pain by spinal
… in the rostroventromedial medulla (RVM) exerts a role in the attenuation of neuropathic pain …

Administrations of thalidomide into the rostral ventromedial medulla alleviates painful diabetic neuropathy in Zucker diabetic fatty rats

Y Yang, Z Zhang, J Guan, J Liu, P Ma, K Gu, J Zhao… - Brain research …, 2016 - Elsevier
… that role of RVM in descending pain modulation, the mechanisms of RVM in the involvement
of diabetic neuropathy, particular in type 2 diabetes neuropathy, are still poorly understood. …

Roles of the rostroventromedial medulla and the spinal 5-HT1A receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat

H Viisanen, A Pertovaara - Neuroscience letters, 2010 - Elsevier
… in neuropathic as well as healthy control animals. We studied whether the rostroventromedial
medulla (… induced by stimulation of M1 in neuropathic animals. Assessments of the noxious …

Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe] NPYF, a neuropeptide FF …

A Pertovaara, U Keski-Vakkuri, J Kalmari, H Wei… - Neuroscience, 2001 - Elsevier
… -neurons of the rostroventromedial medulla may have a role in neuropathy and they may be
… It is proposed that in neuropathy the synaptic effects of descending impulses from medullary

Homo-AMPA in the periaqueductal grey modulates pain and rostral ventromedial medulla activity in diabetic neuropathic mice

E Palazzo, S Boccella, I Marabese, M Perrone… - …, 2022 - Elsevier
… -responding neurons of the rostral ventromedial medulla (RVM), the “pronociceptive” …
diabetic neuropathic mice. Homo-AMPA decreased mechanical allodynia in diabetic neuropathic