Pronociceptive changes in the activity of rostroventromedial medulla (RVM) pain modulatory cells in the streptozotocin-diabetic rat

M Silva, D Amorim, A Almeida, I Tavares… - Brain research …, 2013 - Elsevier
… electrophysiological responses of neurons of the rostroventromedial medulla (RVM), a
key … an increase in the spontaneous activity of RVM pronociceptive ON-like cells in STZ-diabetic …

Pronociceptive changes in response properties of rostroventromedial medullary neurons in a rat model of peripheral neuropathy

L Gonçalves, A Almeida… - European Journal of …, 2007 - Wiley Online Library
… the rostroventromedial medulla (RVM) contribute to neuropathic hypersensitivity. We determined
whether SNI induces changes … were classified into presumably pronociceptive ON-cells …

The rostroventromedial medulla is engaged in the effects of spinal cord stimulation in a rodent model of neuropathic pain

Z Song, OB Ansah, BA Meyerson, A Pertovaara… - Neuroscience, 2013 - Elsevier
… to pinch were considered to be pronociceptive ON-like cells, … ) change in their discharge
rates in response to pinch were defined as neutral cells. This classification scheme of medullary

Pronociception from the dorsomedial nucleus of the hypothalamus is mediated by the rostral ventromedial medulla in healthy controls but is absent in arthritic animals

F Pinto-Ribeiro, D Amorim, A David-Pereira… - Brain Research …, 2013 - Elsevier
… facilitation of pronociceptive cells in the rostroventromedial medulla (… or the discharge rates
of pronociceptive RVM ON- and … In NAIVE and SHAM animals, the changes in nociceptive …

Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity

J Roberts, MH Ossipov… - European Journal of …, 2009 - Wiley Online Library
… Descending facilitation from the rostroventromedial medulla (RVM) is a critical component
in the maintenance of chronic pain states, although the precise mechanisms through which …

Pain modulation from the brain during diabetic neuropathy: uncovering the role of the rostroventromedial medulla

M Silva, JT Costa-Pereira, D Martins, I Tavares - Neurobiology of disease, 2016 - Elsevier
… Given the paramount role of the rostroventromedial medulla (RVM) in descending pain
modulation, this review will mainly focus in this key area of the pain modulatory system in an …

Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy

M Silva, D Martins, A Charrua, F Piscitelli, I Tavares… - …, 2016 - Elsevier
… The rostroventromedial medulla (RVM) plays a key role in conveying to the spinal cord pain
… of inhibitory (antinociceptive) and facilitatory (pronociceptive) effects. In spite of some reports …

Roles of the rostroventromedial medulla and the spinal 5-HT1A receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat

H Viisanen, A Pertovaara - Neuroscience letters, 2010 - Elsevier
… We studied whether the rostroventromedial medulla (RVM) or the spinal 5-HT 1A
receptor contributes to antinociception induced by stimulation of M1 in neuropathic animals. …

Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury

JD Carlson, JJ Maire, ME Martenson… - Journal of …, 2007 - Soc Neuroscience
… pain-facilitating influences from the rostral ventromedial medulla (RVM) in neuropathic
pain, … ,” or “neutral cells” using standard criteria of changes in firing associated with heat-evoked …

Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain

M De Felice, R Sanoja, R Wang, L Vera-Portocarrero… - Pain, 2011 - journals.lww.com
… SNL-induced allodynia was reversed by administration of lidocaine within the rostral
ventromedial medulla (RVM), a site that integrates descending pain modulation via pain inhibitory (…