[HTML][HTML] Rationally designed ruthenium complexes for 1-and 2-photon photodynamic therapy

J Karges, S Kuang, F Maschietto, O Blacque… - Nature …, 2020 - nature.com
… of Ru(II) polypyridine complexes to … Ru(II) polypyridine complexes with a red-shifted 1P
and exceptionally strong 2P absorption using an in silico optimization. The resulting compounds

Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window

E Wachter, DK Heidary, BS Howerton… - Chemical …, 2012 - pubs.rsc.org
Ru(II) 2,2′-biquinoline complexes act as DNA photobinding agents for PDT. While previous
reports of metal complexes … or higher energy blue light, 17 the compounds described here …

Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy

F Heinemann, J Karges, G Gasser - Accounts of chemical …, 2017 - ACS Publications
complex [Ru(bpy) 2 (dppz)] 2+ (bpy = 2,2′-bipyridine; dppz = (dipyrido[3,2-a:2′,3′-c]phenazine),
a series of ruthenium complexes … the affinity of the complexes to DNA but highly …

Ruthenium porphyrin compounds for photodynamic therapy of cancer

F Schmitt, P Govindaswamy, G Süss-Fink… - Journal of medicinal …, 2008 - ACS Publications
… This is demonstrated by the observation that our synthesized ruthenium complexes of
tetrapyridylporphyrin (TPP) are soluble in polar organic solvents, whereas free TPP is nearly …

In vitro evaluation of ruthenium complexes for photodynamic therapy

W Li, Q Xie, L Lai, Z Mo, X Peng, E Leng… - … Photodynamic Therapy, 2017 - Elsevier
… All ruthenium complexes used in this study were synthesized by Prof. Wenjie Mei at School
of Pharmacy, Guangdong Pharmaceutical University (Guangzhou, China). For cell culture, all …

Highly charged ruthenium (II) polypyridyl complexes as effective photosensitizer in photodynamic therapy

L Conti, A Bencini, C Ferrante, C Gellini… - … A European Journal, 2019 - Wiley Online Library
… Based on these results, an optimal design of Ru II polypyridyl systems featuring specific Cu
II ‐… for the development of novel and effective photosensitizers in photodynamic therapy. …

Highly charged ruthenium (II) polypyridyl complexes as lysosome‐localized photosensitizers for two‐photon photodynamic therapy

H Huang, B Yu, P Zhang, J Huang… - Angewandte Chemie …, 2015 - Wiley Online Library
Photodynamic therapy (PDT) is a noninvasive medical … years and been applied for the
treatment of certain types of cancer. … positively charged ruthenium(II) polypyridyl complexes were …

Synthesis, characterization and biological evaluation of mixed-ligand ruthenium (II) complexes for photodynamic therapy

H Huang, P Zhang, B Yu, C Jin, L Ji, H Chao - Dalton Transactions, 2015 - pubs.rsc.org
photodynamic therapy (PDT) and anticancer activity of mixed ligand Ru(II) terpyridyl complexes
… After PDT treatment, mitochondria alteration and nuclear membrane disruption occurred, …

New Ru II pincer complexes: synthesis, characterization and biological evaluation for photodynamic therapy

L Tabrizi, H Chiniforoshan - Dalton Transactions, 2016 - pubs.rsc.org
Three new ruthenium(II) complexes of NCN pincer and phenylcyanamide derivative ligands
of the formula [Ru(L)(Ph2phen)(3,5-(NO2)2pcyd)], 1, [Ru(L)(Me2phen)(3,5-(NO2)2pcyd)], 2, …

[PDF][PDF] An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo

W Sun, S Li, B Häupler, J Liu, S Jin, W Steffen… - Adv. Mater, 2017 - d-nb.info
… ,[3d, 4c] and in addition, light can uncage toxic Ru species or ligands from the complexes
for … of photodynamic therapy and photochemotherapy using photocaged Ru complexes has …