Albumin nanoparticles—A versatile and a safe platform for drug delivery applications

T Zwain, N Taneja, S Zwayen, A Shidhaye… - Nanoparticle …, 2022 - Elsevier
Albumin has an extraordinary ability to bind to lipophilic and other molecules due to its … This
unique property of albumin has been exploited in the design of nanoparticles. Thus, albumin, …

Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy

Z Liu, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
… into albumin nanoparticles. This review article starts with a brief introduction of human serum
albumin (… of serving as a clinically safer platform to deliver hydrophobic drugs in the body. …

[HTML][HTML] Albumin and functionalized albumin nanoparticles: Production strategies, characterization, and target indications

A Srivastava, A Prajapati - Asian Biomedicine, 2020 - sciendo.com
… into the albumin nanoparticles via covalent bonding [19]. … preparing albumin and conjugated
albumin nanoparticles and … , and cytotoxicity of various drug-loaded albumin nanoparticles. …

Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging

JE Lee, MG Kim, YL Jang, MS Lee, NW Kim, Y Yin… - Drug …, 2018 - Taylor & Francis
albumin-based PTX nanoparticles for efficient systemic cancer therapy using a conjugate of
human serum albumin (… HSA-PEG-based nanoparticle can be considered as a safe and long-…

The uniqueness of albumin as a carrier in nanodrug delivery

A Spada, J Emami, JA Tuszynski… - Molecular …, 2021 - ACS Publications
… conjugation of drugs to albumin nanoparticles has also been … as a safety mechanism to
degrade old, damaged, or altered … , used both as an anticancer platform and for the treatment of …

Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles

F Kratz - Journal of controlled release, 2008 - Elsevier
… blood derived albumin, recombinant human serum albumin (… in yeast cells that has shown
comparable safety, tolerability, … the various platform technologies that are based on albumin as …

[HTML][HTML] Strategies for preparing albumin-based nanoparticles for multifunctional bioimaging and drug delivery

FF An, XH Zhang - Theranostics, 2017 - ncbi.nlm.nih.gov
… The in vivo safety of albumin has been demonstrated by its applications in clinical … platform
for NIRF-guided phototherapy 99 , 132 , 133 . ICG-loaded albumin nanoparticles improved …

Albumin and its application in drug delivery

D Sleep - Expert opinion on drug delivery, 2015 - Taylor & Francis
… it an attractive drug delivery platform and the developmental … The safety and general utility
of albumin fusions can be seen … the non-crosslinked albumin nanoparticles. Pharmacokinetic …

Multifunctional albumin nanoparticles as combination drug carriers for intra‐tumoral chemotherapy

M Cui, DJ Naczynski, M Zevon… - Advanced …, 2013 - Wiley Online Library
… , we have presented a new platform of advanced healthcare materials based on albumin
stability of therapeutic cargo, and has led to safer and more effective treatment strategies.25, 26 …

Efficient delivery of therapeutic agents by using targeted albumin nanoparticles

H Kouchakzadeh, MS Safavi… - Advances in protein …, 2015 - Elsevier
… HSA nanoparticles also proved to be effective and safe carriers for the delivery of ganciclovir
(an anticytomegaloviral agent) when administrated by the intravitreal route and did not …