Safety aspects of treatment with lacidipine—a slow-onset, long-acting calcium antagonist

LH Lindholm, P Tcherdakoff, A Zanchetti - Blood pressure, 1996 - Taylor & Francis
Lacidipine was first developed in 1984, with the aim of … to review the clinical safety
profile of lacidipine with the help of … the outcome of calcium antagonist treatment in prospective, …

Safety profile of lacidipine: a review of clinical data

CA Endersby, EG Brown… - Journal of cardiovascular …, 1991 - journals.lww.com
… Summary: The clinical safety of the new dihydropyridine calcium antagonist lacidipine was
assessed in 14 clinical trials, including 1,372 patients treated with lacidipine and 687 treated

Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension

C Rhoda Lee, HM Bryson - Drugs, 1994 - Springer
… blood pressure monitoring, lacidipine 2 to 8mg administered … treatment with lacidipine 2 to
8 mg/dayfor 1 to 4 months in dose-finding studies. When administered once daily, lacidipine 4 …

Safety of the calcium antagonist lacidipine evaluated from a phase III–IV trial database

LH Lindholm, P Tcherdakoff… - Journal of Hypertension, 1996 - journals.lww.com
… In the present analysis, we took lacidipine, a slowonset, long-… we reviewed the clinical safety
profile of lacidipine with the help … data from 16 590 patients treated with lacidipine (Table 1), …

Oral lacidipine in the treatment of anal fissure

L Ansaloni, A Bernabe, R Ghetti, R Riccardi… - Techniques in …, 2002 - Springer
… The aim of this study was to assess the effectiveness of lacidipine, a calcium channel blocker
with a better tolerability in comparison to nifedipine and other calcium antagonists [16, 17], …

Dose linearity of lacidipine pharmacokinetics after single and repeated oral doses in healthy volunteers

LD Ros, L Squassante, S Milleri - Clinical pharmacokinetics, 2003 - Springer
… The human pharmacokinetics of lacidipine were not well characterised using the … on
lacidipine has been published and reports the main characteristics of the compound.[11] Lacidipine

Comparative study of lacidipine and nicidipine SR in the treatment of hypertension: an Italian multicenter study

G Leonetti - Journal of cardiovascular pharmacology, 1991 - journals.lww.com
… Calcium antagonists are effective and safe agents for the treatment of essential hypertension.
They lower elevated blood pressure by reducing the increase in total peripheral resistance…

An assessment of lacidipine and atenolol in mild to moderate hypertension.

D Lyons, G Fowler, J Webster, ST Hall… - British journal of …, 1994 - Wiley Online Library
… 3 Heart rate on treatment with lacidipine alone was significantly … heart disease until shown
to be safe. Finally, with regard to both … These aspects werenot formally examinedin this study, …

Ankle edema formation during treatment with the calcium channel blockers lacidipine and amlodipine: a single-centre study

MB Andrésdóttir, HW van Hamersvelt… - Journal of …, 2000 - journals.lww.com
… The safety profile of the dihydropyridine CCB is generally … lacidipine (4%) than with other
CCB (14%) (3) . In a direct comparison, edema was observed in 10% of patients on lacidipine

Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients

S Taddei, A Virdis, L Ghiadoni, S Uleri, A Magagna… - …, 1997 - Am Heart Assoc
… whether antihypertensive treatment with the calcium antagonist lacidipine can … treatment
at 6 mg/d) lacidipine administration and 2 weeks after withdrawal of chronic (32-week) treatment