Maternal drugs and breastfeeding: Risk assessment from pharmacokinetics to safety evidence-A contribution from the ConcePTION project

E Cardoso, A Monfort, E Ferreira, H Nordeng… - Therapies, 2023 - Elsevier
drug amount through human milk. As population-based evidence is still scarce on safety
of drugs during breastfeeding, risk assessment relies on the little clinical evidence available …

Antipsychotic drugs in pregnancy: a review of their maternal and fetal effects

M Galbally, M Snellen, J Power - … advances in drug safety, 2014 - journals.sagepub.com
evidence for their effects secondary to pregnancy exposure is extremely limited. While this
review does not identify clear evidence for a risk of malformation, there is evidencematernal

Treating the mother–protecting the unborn: the safety of hypoglycemic drugs in pregnancy

C Klieger, E Pollex, G Koren - The Journal of Maternal-Fetal & …, 2008 - Taylor & Francis
… There is evidence of an increase in the prevalence of diabetes among women of childbearing
age … In this context, it is critical to establish the safety of hypoglycemic drugs, both during …

Use and safety of antipsychotic drugs during pregnancy

A Einarson, R Boskovic - Journal of Psychiatric Practice®, 2009 - journals.lww.com
… up-to-date, evidence-based information regarding the safety of antipsychotic drugs that are
maternal treatment. In rats, a decrease in fetal weight and delayed ossification was seen at …

Maternal exposure and neonatal effects of drugs of abuse

JM Barry, AK Birnbaum, LR Jasin… - The Journal of Clinical …, 2021 - Wiley Online Library
evidence available in current research, there is a strong suggestion that fetal development
is affected by prenatal maternal … To date, there is no definitive evidence demonstrating safe

The safety of antimalarial drugs in pregnancy

PA Phillips-Howard, D Wood - Drug safety, 1996 - Springer
maternal disease leads to low birthweight and in the presence of maternal disease substantially
increases the risk of maternal … such drugs, although there has been no human evidence

Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP)

LA Magee, P Mazzotta, G Koren - American journal of obstetrics and …, 2002 - Elsevier
… studies for drug safety in pregnancy and randomized controlled trials for drug effectiveness
for nausea and vomiting in pregnancy. Results: All of the following are safe and effective for …

Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network …

AA Veroniki, P Rios, E Cogo, SE Straus, Y Finkelstein… - BMJ open, 2017 - bmjopen.bmj.com
safety outcomes in infants/children exposed to AEDs in utero or during breast feeding in one
publication, but given the breadth of evidence … The mean maternal age ranged from 24 to 34 …

direct‐acting antivirals for the treatment of HCV during pregnancy and lactation‐implications for maternal dosing, foetal exposure, and safety for mother and child

JJM Freriksen, M van Seyen, A Judd… - Alimentary …, 2019 - Wiley Online Library
… of drug in the foetal or maternal circulation, and as maternal … , the maternal-to-foetal ratio of
total drug plasma concentration … In the absence of conclusive evidence from DAA exposure …

Treatment of bipolar disorders during pregnancy: maternal and fetal safety and challenges

RA Epstein, KM Moore, WV Bobo - … , healthcare and patient safety, 2014 - Taylor & Francis
… accelerated metabolism of it and other drugs owing to the induction of key drug-metabolizing
enzymes. Citation252 There is not yet clear evidence that administering vitamin K analogs …