… of clinical use of three EGFR TKIs (afatinib, gefitinib, and erlotinib). We found that gefitinib
was more commonly used than erlotinib or afatinib in Korea, especially for elderly, which may …

… as the ratio of the risks for the following three comparisons: gefitinib versus afatinib, erlotinib
versus afatinib, and gefitinib versus erlotinib. The Mantel–Haenszel fixed effect method8, 9 …

… trial comparing afatinib with gefitinib on all efficacy and safety outcomes,97 and one
randomized trial comparing afatinib with erlotinib on all efficacy and safety outcomes.103 …

… effectiveness and safety of afatinib, gefitinib, and erlotinib for elderly … and safety of afatinib,
gefitinib, and erlotinib were compared. … For elderly patients, afatinib was more effective, with a …

… , and afatinib is … of afatinib to gefitinib and erlotinib as treatments for patients with advanced
EGFR mutation-positive non-small-cell lung cancer. In addition, we investigated the safety of …

… Thus, we undertook this phase 2b/3 study of afatinib in … 12 weeks of previous erlotinib or
gefitinib treatment, a group for … to be less sensitive to erlotinib and gefitinib. Patients did not need …

… kinase inhibitors (TKIs) erlotinib and gefitinib, patients with … tyrosine kinases, such as afatinib
and dacomitinib, have been … phase III trial recently reported afatinib to be clearly superior …

… currently available EGFR-TKIs (erlotinib, gefitinib, afatinib and icotinib) in treating patients …
et al. had evaluated the efficacy and safety of gefitinib and erlotinib as second-line therapy in …

… that in patients with NSCLC, gefitinib is safe, tolerable, and … is comparable to those of
erlotinib and afatinib, and we can … erlotinib and gefitinib indicates gefitinib's activity and safety …

… among 21 patients receiving sequential gefitinib-erlotinib-afatinib treatment courses (Figure, …
days (Figure, A), we found that afatinib therapy resulted in an earlier onset of paronychia (…