Efficacy and safety of edaravone in treatment of amyotrophic lateral sclerosis—a systematic review and meta-analysis

L Luo, Z Song, X Li, n Huiwang, Y Zeng, n Qinwang… - Neurological …, 2019 - Springer
sclerosis remain controversial. We performed a meta-analysis to evaluate the efficacy and
safety of edaravone … Therefore, we can conclude that edaravone has a favorable safety profile. …

Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis

H Sawada - Expert opinion on pharmacotherapy, 2017 - Taylor & Francis
… A safety analysis revealed no serious adverse events that were considered related to edaravone,
and edaravone is thought to be safeedaravone was safe for use in patients with ALS. …

Safety and efficacy of edaravone in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

M Gao, L Zhu, J Chang, T Cao, L Song, C Wen… - Clinical Drug …, 2023 - Springer
… In this systematic review, the efficacy and safety of edaravone for treating ALS patients were
assessed. This meta-analysis showed that the ALSFRS-R score from baseline to the end of …

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

K Abe, M Aoki, S Tsuji, Y Itoyama, G Sobue… - The Lancet …, 2017 - thelancet.com
… We aimed to substantiate this post-hoc result and assess safety and efficacy of edaravone
in a phase 3 trial that focused on patients with early stage ALS who met the post-hoc analysis …

Safety and effectiveness of long-term intravenous administration of edaravone for treatment of patients with amyotrophic lateral sclerosis

S Witzel, A Maier, R Steinbach, J Grosskreutz… - JAMA …, 2022 - jamanetwork.com
Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis:
a … Safety and efficacy of edaravone in well defined patients with amyotrophic lateral …

Edaravone for the treatment of amyotrophic lateral sclerosis

H Yoshino - Expert Review of Neurotherapeutics, 2019 - Taylor & Francis
… After the safety of 30 mg edaravone administration for 14 days had been confirmed in
ALS patients, 30 mg of edaravone was given for 10 days every month to those patients who …

Safety and efficacy of edaravone compared to historical controls in patients with amyotrophic lateral sclerosis from North-Eastern Italy

…, M Corbetta, G Sorarù, Edaravone Study Group - Journal of the …, 2019 - Elsevier
patients (100) received 60 mg intravenous edaravone with a … observed between patients
treated with edaravone and those … benefit of edaravone in early-stage patients with scores of 2 …

[HTML][HTML] Safety and efficacy of edaravone in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

AZ Nourelden, I Kamal, AI Hagrass, AG Tawfik… - Neurological …, 2023 - Springer
… preliminary indications regarding the effectiveness and safety of edaravone. However, further
… evidence of edaravone regarding efficacy, safety, and survival outcomes in ALS patients. …

[HTML][HTML] Long-term effects of edaravone on survival of patients with amyotrophic lateral sclerosis

M Okada, S Yamashita, H Ueyama, M Ishizaki… - ENeurologicalSci, 2018 - Elsevier
edaravone on ALS patients remain unclear. This study aimed to retrospectively investigate
the long-term effects of edaravone on the survival of ALS patients. … will evaluate the safety and …

[HTML][HTML] Edaravone (Radicava): a novel neuroprotective agent for the treatment of amyotrophic lateral sclerosis

MP Cruz - Pharmacy and Therapeutics, 2018 - ncbi.nlm.nih.gov
… The safety of edaravone in patients with severe renal impairment, end-stage renal disease,
or moderate-to-severe hepatic impairment remains to be studied. Further clinical studies with …