Efficacy and safety of erlotinib in the treatment of metastatic non-small-cell lung cancer

S Ricciardi, S Tomao, F de Marinis - Lung Cancer: Targets and …, 2010 - Taylor & Francis
Lung cancer is the leading cause of cancer deaths worldwide. Targeting the … small-cell lung
cancer (NSCLC) research, treatment, and patient outcome over the last few years. Erlotinib is …

[HTML][HTML] Erlotinib in advanced non-small cell lung cancer: efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study

M Reck, N van Zandwijk, C Gridelli, Z Baliko… - Journal of Thoracic …, 2010 - Elsevier
… advanced non-small cell lung cancer. Here, we report safety and efficacy data from a
large, global, open-label, phase IV trial of erlotinib (Tarceva Lung Cancer Survival Treatment). …

[HTML][HTML] Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… efficacy and safety of erlotinib for non-small cell lung cancer (NSCLC), … erlotinib at 14 sites
(17 departments) in Ibaraki (Japan) between December 2007 and December 2010. The tumor

Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer

JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… on 4068 concentration samples from 1047 patients receiving erlotinib as a single agent or in
erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …

Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a …

T Ciuleanu, L Stelmakh, S Cicenas, S Miliauskas… - The lancet …, 2012 - thelancet.com
Erlotinib, docetaxel, and pemetrexed are approved for the second-line treatment of non-small-cell
lung cancer (… We undertook the Tarceva In Treatment of Advanced NSCLC (TITAN) …

Reviewing the safety of erlotinib in non-small cell lung cancer

M Reck, T Mok, J Wolf, D Heigener… - … opinion on drug safety, 2011 - Taylor & Francis
… advanced pancreatic cancer. The oral administration and manageable toxicity of erlotinib,
along … : This review summarizes safety data from major clinical trials of erlotinib in patients with …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… Non-small cell lung cancer (NSCLC) is one of the leading causes of deaths from cancer
inhibitors (TKIs) such as gefitinib and erlotinib have improved clinical outcomes in patients with …

[HTML][HTML] Efficacy and safety of erlotinib in 1242 East/South-East Asian patients with advanced non-small cell lung cancer

T Mok, Y Wu, JS Au, C Zhou, L Zhang, RP Perng… - Journal of Thoracic …, 2010 - Elsevier
… a distinct safety profile in this population compared with non-Asian patients. We report safety
and … , open-label, phase IV trial of erlotinib (Tarceva Lung Cancer Survival Treatment study). …

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… We argue that safety could not be considered an issue, leaving … clearly demonstrate that
gefitinib is as efficacious as erlotinib. … erlotinib and gefitinib indicates gefitinib's activity and safety

[HTML][HTML] Efficacy and safety of erlotinib in elderly patients in the phase IV POLARSTAR surveillance study of Japanese patients with non-small-cell lung cancer

H Yoshioka, K Komuta, F Imamura, S Kudoh, A Seki… - Lung cancer, 2014 - Elsevier
… with non-small-cell lung cancer (NSCLC). An analysis of the phase IV POLARSTAR
surveillance study examined the safety and efficacy of erlotinib in elderly Japanese patients with …