Efficacy and safety of erlotinib in the treatment of metastatic non-small-cell lung cancer

S Ricciardi, S Tomao, F de Marinis - Lung Cancer: Targets and …, 2010 - Taylor & Francis
Lung cancer is the leading cause of cancer deaths worldwide. Approximately 400,000 new
cases of lung cancer are diagnosed every year in Europe; lungcancers in men. Citation1 …

Reviewing the safety of erlotinib in non-small cell lung cancer

M Reck, T Mok, J Wolf, D Heigener… - … opinion on drug safety, 2011 - Taylor & Francis
… advanced pancreatic cancer. The oral administration and manageable toxicity of erlotinib,
along … : This review summarizes safety data from major clinical trials of erlotinib in patients with …

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
safety of erlotinib for non-small cell lung cancer (NSCLC), we performed a population-based
observational study. The study involved 307 patients treated with erlotinib … received erlotinib

[HTML][HTML] Erlotinib in advanced non-small cell lung cancer: efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study

M Reck, N van Zandwijk, C Gridelli, Z Baliko… - Journal of Thoracic …, 2010 - Elsevier
… There were no unexpected safety findings relating to erlotinib in this study. As the prespecified
expected treatment-related AEs were not recorded (unless they resulted in premature …

[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study

K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
… The aim of this study was to evaluate the efficacy and safety of Erlotinib in Japanese
patients with previously treated non-small cell lung cancer (NSCLC). Available tumor biopsy …

Efficacy and safety of first-line erlotinib in elderly patients with advanced non-small cell lung cancer

O Merimsky, CK Cheng, JSK Au… - Oncology …, 2012 - spandidos-publications.com
… that in this analysis of elderly patients receiving erlotinib in the first-line setting, no new
safety signals were identified. The most common AE seen with erlotinib is skin rash, but this is …

Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer

JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… on 4068 concentration samples from 1047 patients receiving erlotinib as a single agent or in
erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… III study comparing gefitinib with erlotinib. It did not demonstrate statistical non inferiority of
gefitinib in terms of PFS compared with erlotinib [7]. The LUX-Lung 7 trial compared afatinib …

Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a …

T Ciuleanu, L Stelmakh, S Cicenas, S Miliauskas… - The lancet …, 2012 - thelancet.com
… 409 patients were included in the safety population: 196 in the erlotinib group and 213 in
the chemotherapy group. 46 (23%) of 196 patients in the erlotinib group were treated for 0–30 …

[HTML][HTML] Efficacy and safety of erlotinib in elderly patients in the phase IV POLARSTAR surveillance study of Japanese patients with non-small-cell lung cancer

H Yoshioka, K Komuta, F Imamura, S Kudoh, A Seki… - Lung cancer, 2014 - Elsevier
… The safety population comprised all patients who received erlotinib and had a case report
… included in the safety population, except those where erlotinib therapy was prescribed off-…