[HTML][HTML] Efficacy and safety of pyrotinib in advanced lung adenocarcinoma with HER2 mutations: a multicenter, single-arm, phase II trial

Z Song, Y Li, S Chen, S Ying, S Xu, J Huang, D Wu… - BMC medicine, 2022 - Springer
… Collectively, our results revealed variable efficacy of pyrotinib in NSCLC patients with
different HER2 mutations and warrant further validation in larger randomized clinical trials. …

Retrospective Study on the Efficacy and Safety of Pyrotinib‐Based Therapy for HER2‐Positive Nonbreast Advanced Solid Tumors

J Wang, B Zhang, X Cheng, Q Li, H Lv, C Nie… - Journal of …, 2022 - Wiley Online Library
… patients with HER2 amplification or mutations who were … pyrotinib in other HER2-positive
solid tumors. This research explored the efficacy and safety of pyrotinib in the treatment of HER2

Safety and efficacy of pyrotinib for HER2‑positive breast cancer in the neoadjuvant setting: A systematic review and meta‑analysis

Q Ma, B Wei, BC Wang, G Wang… - Oncology …, 2024 - spandidos-publications.com
… patients with HER2‑positive breast cancer had PIK3CA mutations, … analyses on pyrotinib in
patients with advanced HER2‑… the safety and efficacy of pyrotinib in neoadjuvant therapy for …

[HTML][HTML] Effectiveness and safety of pyrotinib, and association of biomarker with progression-free survival in patients with HER2-positive metastatic breast cancer: a …

Q Chen, D Ouyang, M Anwar, N Xie, S Wang… - Frontiers in …, 2020 - frontiersin.org
HER2-positive MBC who were treated with pyrotinib, this study aimed to evaluate the effects
on PFS of the pyrotinib … In addition to individual mutations, this study evaluated the overall …

Safety and efficacy of inetetamab in combination with pyrotinib in HER2 mutant patients with non-small cell lung cancer (NSCLC): An open-label, phase Ib trial.

W Fang, Y Zhao, Y Huang, Y Zhang, S Hong, Y Huang… - 2023 - ascopubs.org
… of pyrotinib in advanced NSCLC patients with HER2 mutations. Inetetamab is a recombinant
humanized anti-HER2 … combined with pyrotinib could show manageable safety and more …

MA04. 03 preliminary results of a phase II study about the efficacy and safety of pyrotinib in patients with HER2 mutant advanced NSCLC

S Ren, C Zhou, G Gao, C Su, X Chen, FY Wu, X Li… - Journal of Thoracic …, 2017 - jto.org
… , 11 patients with her2 mutated advanced NSCLC were … pyrotinib as the first line therapy
and the median previous anti-cancer regimen was 2. 9 patients had the details variants of HER2

Studies on the safety and efficacy of pyrotinib in the treatment of HER2-positive advanced solid tumors excluding breast cancer

Y Yin, H Yang, Z Liu, J Tan, C Zhu, M Chen… - Cancer management …, 2020 - Taylor & Francis
… Citation14 Multiple clinical studies have confirmed the promising efficacy of pyrotinib in breast
cancer, so this study investigated the safety and efficacy of pyrotinib in HER2-positive non-…

[HTML][HTML] Mechanism, safety and efficacy of three tyrosine kinase inhibitors lapatinib, neratinib and pyrotinib in HER2-positive breast cancer

JC Xuhong, XW Qi, Y Zhang, J Jiang - American journal of cancer …, 2019 - ncbi.nlm.nih.gov
… improved the prognosis of patients with HER2-positive breast cancer. … HER2 breast cancer,
namely, lapatinib, neratinib and pyrotinib, and systematically reviews the mechanism, safety, …

Efficacy of anti-HER2 drugs in the treatment of patients with HER2-mutated cancers: a systematic review and meta-analysis

Y Zheng, G Shen, C Zhang, X Huo, Y Xin… - Clinical and …, 2023 - Springer
… anti-HER2 therapeutic agents. In this meta-analysis of heavily pretreated patients with HER2
mutations, anti-HER2 … In addition, pyrotinib has shown good efficacy and a tolerable safety

[HTML][HTML] Molecular correlation of response to pyrotinib in advanced NSCLC with HER2 mutation: biomarker analysis from two phase II trials

S Mao, S Yang, X Liu, X Li, Q Wang, Y Zhang… - … Hematology & Oncology, 2023 - Springer
… : n = 60) which evaluated the efficacy and safety of pyrotinib in HER2-mutant advanced lung
… treatment of pyrotinib in patients with HER2 mutation. We found that TP53 mutations could …