Efficacy and safety of sarilumab in hospitalized patients with coronavirus disease 2019: a randomized clinical trial

S Sivapalasingam, DJ Lederer, R Bhore… - … Infectious Diseases, 2022 - academic.oup.com
… with coronavirus disease 2019 (COVID-19) receiving corticosteroids. This study evaluated
the efficacy and safety of sarilumab, … , in the treatment of hospitalized patients with COVID-19. …

Efficacy and safety of sarilumab in COVID‐19: a systematic review

R Chamlagain, S Shah… - … Infectious Diseases, 2021 - Wiley Online Library
… the treatment of COVID-19. We aim to assess the role of sarilumab in the treatment of COVID-19
… , but there were no significant differences among the comparison and sarilumab group. …

A comprehensive review on sarilumab in COVID-19

S Khiali, A Rezagholizadeh… - Expert Opinion on …, 2021 - Taylor & Francis
… of SARS-CoV-2 related acute respiratory distress syndrome (ARDS) and MOD, we reviewed
the current evidence regarding the safety and efficacy of the sarilumab administration in the …

Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a …

RL López, SC Fernández, LL Pérez, AR Palacios… - BMJ open, 2020 - bmjopen.bmj.com
… It is a safe and well-tolerated drug.8 The most common … safety of early treatment with
sarilumab added to standard treatment to prevent progression to severe pulmonary forms of COVID

[HTML][HTML] Efficacy and safety of sarilumab in patients with COVID19 pneumonia: a randomized, phase III clinical trial (SARTRE study)

A Sancho-López, AF Caballero-Bermejo… - Infectious diseases and …, 2021 - Springer
coronavirus disease 2019 (COVID-19). High Interleukin-6 (IL6) blood levels have been identified
in severe COVID-19 disease… support the safety of the use of sarilumab in this indication. …

Early use of sarilumab in patients hospitalized with COVID-19 pneumonia and features of systemic inflammation: the SARICOR randomized clinical trial

N Merchante, S Cárcel, JC Garrido-Gracia… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
safety of early treatment with sarilumab, added to standard of care (SOC), in hospitalized
adults with COVID… trial of hospitalized patients with COVID-19 pneumonia and interleukin (IL)-6 …

[HTML][HTML] Drug-induced liver injury following the use of tocilizumab or sarilumab in patients with coronavirus disease 2019

Q Gao, X Yin, B Tan, J Wang, J Chen, B Zhao… - … Infectious Diseases, 2022 - Springer
COVID-19 patients. We analyzed DILI cases associated with tocilizumab or sarilumab in
treating COVID-… Disproportionality analysis and Bayesian analysis of COVID-19 patients were …

Clinical efficacy and safety of interleukin-6 receptor antagonists (tocilizumab and sarilumab) in patients with COVID-19: a systematic review and meta-analysis

SY Yu, DH Koh, M Choi, S Ryoo, K Huh… - Emerging microbes & …, 2022 - Taylor & Francis
… This study investigated the efficacy and safety of interleukin-6 (IL-6) receptor antagonists
with standard care treatment in patients with coronavirus disease 2019 (COVID-19). The …

A randomized placebo-controlled trial of sarilumab in hospitalized patients with Covid-19

…, DM Weinreich, Sarilumab-COVID-19 Study Team - MedRxiv, 2021 - medrxiv.org
… trial, we systematically collected all SAEs and AESIs providing important safety information
of the use of sarilumab of doses up to 800 mg in the hospitalized Covid-19 population. …

[HTML][HTML] Sarilumab administration in COVID-19 patients: Literature review and considerations

A Marino, A Munafò, E Augello, CM Bellanca… - Infectious Disease …, 2022 - mdpi.com
… In summary, sarilumab is a safe drug with good clinical outcomes in patients with COVID-19 …
assess the efficacy and safety of this therapeutic approach to achieve improved outcomes in …