Efficacy and safety of sarilumab in hospitalized patients with coronavirus disease 2019: a randomized clinical trial

S Sivapalasingam, DJ Lederer, R Bhore… - Clinical Infectious …, 2022 - academic.oup.com
… (IL)-6R therapies in hospitalized patients with coronavirus disease 2019 (COVID-19) …
safety of sarilumab, an anti–IL-6R monoclonal antibody, in the treatment of hospitalized patients

A randomized placebo-controlled trial of sarilumab in hospitalized patients with Covid-19

…, DM Weinreich, Sarilumab-COVID-19 Study Team - MedRxiv, 2021 - medrxiv.org
… or sarilumab may improve clinical outcomes in patients with Covid-19, … safety of intravenous
(IV) sarilumab, an anti–IL-6R monoclonal antibody, for the treatment of hospitalized patients

Efficacy and safety of sarilumab in COVID‐19: a systematic review

R Chamlagain, S Shah… - Interdisciplinary …, 2021 - Wiley Online Library
… the role of sarilumab. In this review, we aim to analyze the role of the … , sarilumab, in the
treatment of COVID-19 patients. … Sarilumab may reduce the number of days of hospitalization. …

Long-term safety and efficacy of sarilumab over 5 years in patients with rheumatoid arthritis refractory to TNF inhibitors

R Fleischmann, MC Genovese, K Maslova… - …, 2021 - academic.oup.com
Objective The objective of this study was to evaluate the long-term safety and efficacy of
sarilumab over 5 years in patients with RA refractory to TNF inhibitors (TNFis). Methods Patients

Long-term safety of sarilumab in rheumatoid arthritis: an integrated analysis with up to 7 years' follow-up

R Fleischmann, MC Genovese, Y Lin, G St John… - …, 2020 - academic.oup.com
… AEs that required inpatient hospitalization or prolongation of existing hospitalization) and …
Serious infections were defined as infections requiring hospitalization and/or intravenous …

Long-term safety and efficacy of sarilumab with or without background csDMARDs in rheumatoid arthritis

GR Burmester, V Strand, AJ Kivitz, CC Hu… - …, 2023 - academic.oup.com
… Long-term sarilumab treatment with/without csDMARDs in patients with RA revealed no
new safety findings. Efficacy and HRQOL were maintained or further increased over the open-…

Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial

FX Lescure, H Honda, RA Fowler, JS Lazar… - The Lancet …, 2021 - thelancet.com
… We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor inhibitor, in
patients with severe (requiring supplemental oxygen by nasal cannula or face mask) or critical …

Early use of sarilumab in patients hospitalized with COVID-19 pneumonia and features of systemic inflammation: the SARICOR randomized clinical trial

N Merchante, S Cárcel, JC Garrido-Gracia… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
safety of early treatment with sarilumab, added to standard of care (SOC), in hospitalized
, randomized, controlled clinical trial of hospitalized patients with COVID-19 pneumonia and …

Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a …

RL López, SC Fernández, LL Pérez, AR Palacios… - BMJ open, 2020 - bmjopen.bmj.com
… the efficacy and safety of the administration of two doses of sarilumab (200 … safety will be
monitored up to 28 days postadministration. A total of 120 patients will be recruited (40 patients

Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a …

AF Caballero Bermejo, B Ruiz-Antorán… - Trials, 2020 - Springer
… with sarilumabpatients with interstitial pneumonia. This study will also provide supportive
evidence to that provided by currently ongoing studies on the efficacy and safety of sarilumab