… Temozolomide (TMZ) often is used as adjuvant or first-line therapy for patients with glioma.
… Subsequent salvage therapies are reported to have limited efficacy at the time of disease …

… patients reported good response to temozolomide treatment in three (38%) and two cases
(29%) respectively (22, 23). In the latter study, four additional patients … observed in Patients #3 …

… We investigated the response, survival, and correlation with MGMT promoter methylation
in a cohort of patients with adult intracranial ependymoma receiving TMZ as salvage therapy …

… To our knowledge, this patient is the first one with primary brain lymphoma who … temozolomide.
The rapid and complete response suggests a potential therapeutic role for temozolomide. …

… included patients in this study received one of the salvage … and conventional temozolomide
administration). CCRT = … may be important to the salvage therapy, but was not available …

… Similar to CCNU salvage therapy used in the current study, median radiographic
response was 22.5 %, median PFS was 4.1 months and PFS-6 was 40 %. It therefore seems …

… II trial of temozolomide as salvage therapy for PCNSL was … any salvage therapy in most
of the non-responding patients. … response rate of salvage treatment in patients with PCNSL …

… temozolomide.29, 30 In a metaanalysis of patients in Phase II trials,11 patients receiving
salvage … before study entry fared worse than did patients receiving fewer interventions (PFS rate …

… of the alkylating agent temozolomide in immunocompetent patients with recurrent primary …
temozolomide 150 mg m −2 day −1 , for 5 days every 4 weeks was administered to 36 patients …

… All patients had previously been treated with surgery, concurrent radiotherapy and
temozolomide, post-radiotherapy temozolomide and in 34 patients, one salvage regimen (PCV: 21, …