Physiological roles of SAPK/JNK signaling pathway

H Nishina, T Wada, T Katada - Journal of Biochemistry, 2004 - academic.oup.com
… Stress-activated protein kinase/c-Jun NH 2 -terminal kinase (SAPK/JNK) is activated by …
of SAPK/JNK activation in embryonic development in addition to immune responses. SAPK/JNK

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis

M Verheij, GA Ruiter, SF Zerp… - Radiotherapy and …, 1998 - Elsevier
… , osmotic/oxidative stress and protein synthesis inhibition) and leads to activation of a
stress-activated protein kinase, also known as c-Jun N-terminal kinase (SAPK/JNK), and p38, …

Activation of SAPK/JNK signaling by protein kinase Cδ in response to DNA damage

K Yoshida, Y Miki, D Kufe - Journal of Biological Chemistry, 2002 - ASBMB
… activation of protein kinase Cδ (PKCδ). … protein kinase (SAPK/JNK) in cells treated with
1-β-d-arabinofuranosylcytosine (araC) and other genotoxic agents. DNA damage-induced SAPK

[HTML][HTML] A novel SAPK/JNK kinase, MKK7, stimulated by TNFα and cellular stresses

T Moriguchi, F Toyoshima, N Masuyama… - The EMBO …, 1997 - embopress.org
… of MAPK‐related kinases, called stress‐activated protein kinase (SAPK)/c‐Jun N‐terminal …
for SAPK/JNK in vivo, we performed immunoblotting and immune complex kinase assays in …

HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway.

F Kiefer, LA Tibbles, M Anafi, A Janssen… - The EMBO …, 1996 - embopress.org
… the SAPK/JNK pathway. We demonstrate that HPK1 activates SAPK via the mixed lineage
kinase … These data establish a novel pathway to SAPK activation, demonstrating integration of …

MAPK kinase kinase regulation of SAPK/JNK pathways

L Stalheim, GL Johnson - Stress-activated protein kinases, 2007 - Springer
SAPK/JNK members of the MAPK family are regulated by at least fourteen known MAPK
kinase kinases … -activated protein kinase/extracellular signal-regulated kinase kinase binding …

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and …

Y FLEMING, CG ARMSTRONG, N MORRICE… - Biochemical …, 2000 - portlandpress.com
protein kinase-1 (SAPK1) or c-Jun N-terminal kinase (JNK) is activated synergistically in
itro by MKK4 [also called SAPK or extracellular-signal-regulated kinase (ERK) kinase (SEK), …

Early modifications in the expression of mitogen-activated protein kinase (MAPK/ERK), stress-activated kinases SAPK/JNK and p38, and their phosphorylated …

I Ferrer, B Friguls, E Dalfó, AM Planas - Acta neuropathologica, 2003 - Springer
… Tyr204 of p44 and p42 MAP kinases (ERK1 and ERK2), but … tyrosine of either JNK/SAPK
or p38 MAP kinase homologues. … phospho-SAPK/JNK (Thr183/Tyr185) antibody (SAPK/JNK-P; …

Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling

A Atfi, S Djelloul, E Chastre, R Davis… - Journal of Biological …, 1997 - ASBMB
… stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) … SAPK/JNK signaling
pathways including Rho-like GTPases, mitogen-activated protein kinase (MAPK) kinase kinase

Expression of stress‐activated kinases c‐Jun N‐terminal kinase (SAPK/JNK‐P) and p38 kinase (p38‐P), and tau hyperphosphorylation in neurites surrounding βA …

B Puig, T Gómez‐Isla, E Ribe… - Neuropathology and …, 2004 - Wiley Online Library
protein kinase and extracelullar signal-regulated kinase (MAPK/ERK-P) occurs in a few amyloid
plaques. However, strong expression of SAPK/JNK-… for βA and stress kinases. Moreover, …