… coronavirus 2 (SARS-CoV-2) that uses live-attenuated yellow fever 17D (YF17D) vaccine
as a vector to express a noncleavable prefusion form of the SARS-CoV-2 … of SARS-CoV-2 …

… SARS-CoV-2 WT and Delta in both nasal turbinates and lungs, and induced substantially
attenuated … Omicron variant has attenuated pathogenicity compared with SARS-CoV-2 WT and …

… and than an ancestral strain of SARS-CoV-2. Although the spike (… 2,3 , the Omicron S
protein was less efficiently cleaved compared to the S proteins of Delta and ancestral SARS-CoV-2. …

… only live attenuated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
… Except for the furin cleavage site deletion, the COVI-VAC and parental SARS-CoV-2 amino …

… —SARS-CoV-2 to attenuate it based on a literature search. The obtained results were analyzed
to determine the potential features of attenuated SARS-CoV-2 … on attenuated COVID-19 …

… -2) would be very useful for COVID-19 research and countermeasure development. Here we
report a highly attenuated SARS-CoV-2 (… as a live-attenuated vaccine platform and a BSL-2 …

… over time (ii). What makes the current pandemic unique is that, thanks to … SARS-CoV-2
evolves while it spreads. We argue that knowledge of naturally emerging attenuated SARS-CoV-2 …

… attenuation in hamsters seen by our group and others 43 was also surprising, given that other
SARS-CoV-2 … Our results showing attenuated B.1.1.529 infection in laboratory mice do not …

… to SARS-CoV-2 pathogenicity. We show that S, the most mutated protein in Omicron, has an
incomplete role in Omicron attenuation… , the virus exhibited an attenuated phenotype largely …

… the SARS-CoV-2 spike (S) protein are a goal of COVID-19 … , we exposed a VSV-eGFP-SARS-CoV-2-S
chimeric virus, in which … SARS-CoV-2 revealed substitutions that may attenuate …