SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
… location of the mutation and the affinity … SARS-CoV-2 mutations and the viral variations
is conducted. In the light of current knowledge, the various disguises of the mutant SARS-CoV-2

[HTML][HTML] Mutations and evolution of the SARS-CoV-2 spike protein

N Magazine, T Zhang, Y Wu, MC McGee, G Veggiani… - Viruses, 2022 - mdpi.com
… by which the common mutations on the spike protein that … these mutations within the
context of the SARS-CoV-2 spike … the effects of future mutations along SARS-CoV-2 evolution. …

Mutations strengthened SARS-CoV-2 infectivity

J Chen, R Wang, M Wang, GW Wei - Journal of molecular biology, 2020 - Elsevier
… -angiotensin-converting enzyme 2 binding free energy changes. … mutations on the S
protein receptor-binding domain, we show that most likely future mutations will make SARS-CoV-2

[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
… of mutations. In this Review, we summarize the literature on mutations of the SARS-CoV-2
discuss them in the context of observed mutation frequencies in global sequence datasets. …

[HTML][HTML] Geographic and genomic distribution of SARS-CoV-2 mutations

D Mercatelli, FM Giorgi - Frontiers in microbiology, 2020 - frontiersin.org
… In the present study, we gather the 48,635 SARS-CoV-2SARS-CoV-2 mutations compared
with the reference Wuhan genome NC_045512.2, observing an average of 7.23 mutations

[HTML][HTML] The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
SARS-CoV-2 mutations and the correlates of protective immunity against variants with these
mutations. … Therefore, in this Review, we use the term mutation to indicate an amino acid …

[HTML][HTML] The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity

Q Li, J Wu, J Nie, L Zhang, H Hao, S Liu, C Zhao… - Cell, 2020 - cell.com
… ) as well as mutants at the putative N-linked glycosylation sites in the SARS-CoV-2 S protein.
To achieve these, we generated 106 S mutants reported in the public domain or mutants at …

[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges

JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
… Various mutants of SARS-CoV-2 arrived, mainly concerned with the spike protein, a key … be
checked in different SARS-CoV-2 mutants. We discussed all mutants of SARS-CoV-2 and the …

Genetic variants of SARS-CoV-2—what do they mean?

AS Lauring, EB Hodcroft - Jama, 2021 - jamanetwork.com
… The D614G mutation in the spike glycoprotein of SARS-CoV-2 was first detected at a
significant level in early March 2020 and spread to global dominance over the next month. The …

Emergence of genomic diversity and recurrent mutations in SARS-CoV-2

L Van Dorp, M Acman, D Richard, LP Shaw… - Infection, Genetics and …, 2020 - Elsevier
… By focusing on mutations which have emerged independently multiple times (homoplasies), …
recurrent mutations in the SARS-CoV-2 genome. Nearly 80% of the recurrent mutations