SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens

L Bartolo, S Afroz, YG Pan, R Xu, L Williams… - Science …, 2022 - science.org
… Our data revealed a substantial number of SARS-CoV-2–… cross-reacted with antigens from
commensal bacteria in the … to sequences from endemic coronavirus and commensal bacteria. …

[HTML][HTML] Cross-regulation of antibody responses against the SARS-CoV-2 spike protein and commensal microbiota via molecular mimicry

M Bondareva, L Budzinski, P Durek, M Witkowski… - Cell Host & Microbe, 2023 - cell.com
… The commensal microflora provides a repertoire of antigens that illicit mucosal antibodies. …
antigens. We demonstrate that the oral microbiota can induce salivary anti-SARS-CoV-2 …

[HTML][HTML] Hacking commensal bacteria to consolidate the adaptive mucosal immune response in the gut–lung axis: future possibilities for SARS-CoV-2 protection

M Pereira, JK Oh, DK Kang, L Engstrand, VD Valeriano - BioTech, 2022 - mdpi.com
… Given the ongoing pandemic, many research groups have designed and tested such RV
platform designs to display predicted antigenic epitopes from the Spike S protein of SARS-CoV-…

Preexisting antibodies targeting SARS-CoV-2 S2 cross-react with commensal gut bacteria and impact COVID-19 vaccine induced immunity

L Jia, S Weng, J Wu, X Tian, Y Zhang, X Wang… - Gut …, 2022 - Taylor & Francis
… Citation13–15 Besides, autoimmune diseases caused by cross-reactivities between microbial
and self-antigens also implied that commensal gut bacteria represent important sources of …

Induction of cross-reactive antibody responses against the RBD domain of the spike protein of SARS-CoV-2 by commensal microbiota

J Ninnemann, L Budzinski, M Bondareva, M Witkowski… - Biorxiv, 2021 - biorxiv.org
… The commensal microflora is a source for multiple antigens that may induce cross-reactive …
against SARS-CoV-2 remains unknown. Here we report that several commensal bacteria …

[HTML][HTML] An update on the mutual impact between SARS-CoV-2 infection and gut microbiota

S Li, Y Zhou, D Yan, Y Wan - Viruses, 2022 - mdpi.com
SARS-CoV-2 and commensal bacteria, which represents a previously overlooked connection
between COVID-19 and commensal … -react with commensal gut microbial antigens [139]. …

[HTML][HTML] On the molecular determinants of the SARS-CoV-2 attack

D Kanduc, Y Shoenfeld - Clinical Immunology (Orlando, Fla.), 2020 - ncbi.nlm.nih.gov
… to the SARS-CoV-2-associated lung diseases. The data warn against using vaccines based
on entire SARS-CoV-2 antigens to fight SARS-CoV … for effective anti-CoV immunotherapy [3]. …

Pre-existing antibodies targeting a linear epitope on SARS-CoV-2 S2 cross-reacted with commensal gut bacteria and shaped vaccine induced immunity

L Jia, S Weng, J Wu, X Tian, Y Zhang, X Wang, J Wang… - medRxiv, 2021 - medrxiv.org
… to certain commensal gut bacteria (13–15). Besides, autoimmune diseases caused by
cross-reactivities between microbial and self-antigens also implied that commensal gut bacteria …

[HTML][HTML] Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination

ES Geanes, C LeMaster, ER Fraley, S Khanal… - Scientific Reports, 2022 - nature.com
SARS-CoV-2 spike S2 subunit epitopes could cross-react with commensal gut bacteria
proteins that may prime SARS-CoV… antibody response to each SARS-CoV-2 antigen. Using the …

[HTML][HTML] Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

N Smith, P Goncalves, B Charbit, L Grzelak… - Nature …, 2021 - nature.com
… of commensal … as target antigens the extracellular domain of the spike protein in the form
of a trimer (ELISA tri-S), and the S-Flow assay, which is based on the recognition of SARS-CoV-…