Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection
… , measuring these functions is … effector functions in the context of SARS-CoV-2 infection,
and we discuss the implications of these data for the development of next-generation SARS-CoV-…
and we discuss the implications of these data for the development of next-generation SARS-CoV-…
[HTML][HTML] Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
… The recombinant virus, mouse-adapted SARS-CoV-2 (SARS-CoV-2 … effector function,
and antibody combinations on protection from SARS-CoV-2 MA infection in mice and SARS-CoV…
and antibody combinations on protection from SARS-CoV-2 MA infection in mice and SARS-CoV…
Deciphering Fc-effector functions against SARS-CoV-2
G Beaudoin-Bussières, A Finzi - Trends in Microbiology, 2024 - cell.com
… effector functions. Here, we review these assays and what is known regarding anti-SARS-CoV-2
Fc-effector … current state of knowledge regarding anti-SARS-CoV-2 Fc-effector functions. …
Fc-effector … current state of knowledge regarding anti-SARS-CoV-2 Fc-effector functions. …
Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccination
X Tong, RP McNamara, MJ Avendaño… - Nature …, 2023 - nature.com
… While FcR binding is required to initiate Fc-effector function, we next sought to profile the …
vaccine platforms, focused on the WT and Omicron SARS-CoV-2 Spike antigens. Although the …
vaccine platforms, focused on the WT and Omicron SARS-CoV-2 Spike antigens. Although the …
[HTML][HTML] Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
… (mAbs) in SARS-CoV-2-infected animals. Whereas Fc effector functions are dispensable when
… When given after infection, intact mAbs reduce SARS-CoV-2 burden and lung disease in …
… When given after infection, intact mAbs reduce SARS-CoV-2 burden and lung disease in …
Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2
… To begin to evaluate the contribution of Fc effector functions to antibody protection against
SARS-CoV-2 infection, we profiled vaccine-induced antibodies from sera pooled from …
SARS-CoV-2 infection, we profiled vaccine-induced antibodies from sera pooled from …
Research progress in Fc‐effector functions against SARS‐CoV‐2
R Gao, C Feng, Z Sheng, F Li… - Journal of Medical …, 2024 - Wiley Online Library
… Fc-effector functions play a crucial role in combating SARS-CoV-2 … of Fc-effector functions
in broadly disarming SARS-CoV-2 … antibody function to develop an effective SARS-CoV-2 …
in broadly disarming SARS-CoV-2 … antibody function to develop an effective SARS-CoV-2 …
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser… - Cell host & …, 2021 - cell.com
… SARS-CoV-2 naive individuals but strong anti-receptor binding domain and spike antibodies
with Fc-mediated effector functions … of Fc-mediated effector functions and T cell responses …
with Fc-mediated effector functions … of Fc-mediated effector functions and T cell responses …
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the …
CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres… - PLoS …, 2021 - journals.plos.org
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19,
little is known about their mechanism(s) of action or effective dosing windows. We report …
little is known about their mechanism(s) of action or effective dosing windows. We report …
mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern
P Kaplonek, S Fischinger, D Cizmeci, YC Bartsch… - Immunity, 2022 - cell.com
… Thus, we aimed to define whether Fc effector functions were equally disrupted across
VOCs. Given the ability of VOCs to re-infect previously naturally immune individuals ( …
VOCs. Given the ability of VOCs to re-infect previously naturally immune individuals ( …
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