[HTML][HTML] Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

MJ Vincent, E Bergeron, S Benjannet, BR Erickson… - Virology journal, 2005 - Springer
… antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed
… This may negatively influence the virus-receptor binding and abrogate the infection, with …

[HTML][HTML] Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs

ELC Tan, EE Ooi, CY Lin, HC Tan, AE Ling… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
SARS-CoV has been shown to infect Vero E6 cells, an … the only in vitro model of SARS-CoV
infection. The initial screen was … exhibit in vitro inhibitory activity against SARS-CoV and are …

[HTML][HTML] Anti-SARS-CoV natural products with the potential to inhibit SARS-CoV-2 (COVID-19)

S Verma, D Twilley, T Esmear… - Frontiers in …, 2020 - frontiersin.org
… This review focuses on natural products, which have shown activity against SARS-CoV, as
a selection criterion for potential inhibition of SARS-CoV-2, due to the genome similarity and …

Inhibitors of SARS-CoV-2 entry: current and future opportunities

S Xiu, A Dick, H Ju, S Mirzaie, F Abdi… - Journal of medicinal …, 2020 - ACS Publications
… efforts in designing entry inhibitors against SARS-CoV, MERS-CoV, and other coronaviruses
that can provide important information to combat the current SARS-CoV-2 outbreak. …

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

BJ Bosch, BEE Martina… - Proceedings of the …, 2004 - National Acad Sciences
… as inhibitors of SARS-CoV infection of Vero cells. It appeared that HR2 peptides, but not HR1
peptides, were inhibitory… murine coronavirus mouse hepatitis virus (MHV) in inhibiting MHV …

Potential antivirals and antiviral strategies against SARS coronavirus infections

E De Clercq - Expert review of anti-infective therapy, 2006 - Taylor & Francis
… However, in none of these cases Citation[30–37] was it ascertained whether the compounds
were also effective in inhibiting SARS-CoV infection in cell culture, except for two of the …

[HTML][HTML] Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro

N Clementi, C Scagnolari, A D'Amore… - Pharmacological …, 2021 - ncbi.nlm.nih.gov
… Vero E6 cells were infected with SARS-CoV-2 (MOI:0.01) and monitored for the presence of
… to the external medium, we observed that SARS-CoV-2 infection was inhibited in a time- and …

[HTML][HTML] Inhibition of SARSCoV-2 by type I and type III interferons

U Felgenhauer, A Schoen, HH Gad, R Hartmann… - Journal of Biological …, 2020 - ASBMB
… Because virus inhibition by an IFN inhibitor seems counterintuitive, we aimed to clarify the …
on SARSCoV-2 replication. Cells were pretreated with 1 μm ruxolitinib for 16 h and infected

[HTML][HTML] Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high …

S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao… - Cell research, 2020 - nature.com
inhibiting infection of the novel β-CoV, SARS-CoV-2. We then optimized EK1 peptide in hopes
of improving its fusion inhibitory … and 149-fold more potent against SARS-CoV-2 S protein-…

Inhibition of SARS-CoV replication by siRNA

CJ Wu, HW Huang, CY Liu, CF Hong, YL Chan - Antiviral research, 2005 - Elsevier
… siRNAs against SARS-CoV leader, TRS, … SARS-CoV infection. We demonstrate that siRNAs
directed against Spike sequences and the 3′-UTR can inhibit the replication of SARS-CoV