… sequences revealed that the SARS-CoV N protein contains a putative nuclear export signal
(NES) located at position 220–231 and three putative classical nuclear localization signals (…

… SARS-CoV-2-induced OS triggers activation of different signaling pathways such as nuclear
factor erythroid 2-related factor 2 (… was to elucidate the role of Nrf2 in SARS-CoV-2 infection. …

… SARS-associated coronavirus (SARS-CoV) causes inflammation and damage to the lungs …
the roles of SARS-CoV proteins in regulation of the proinflammatory factor, cyclooxygenase-2 …

… the nuclear translocation of IRF3, nuclear factor-κB (NF-κB), and STATs. To date, the following
proteins of SARS-CoV-… Additionally, we also elaborated the perspectives of SARS-CoV-2 …

… coronavirus 2 (SARS-CoV-2) and is associated with a significant increase in morbidity and
mortality. The present review discusses nuclear factor-… of NF-κB in SARS-CoV-2 have been …

… Finally, to determine whether Nup98 is the critical factor hijacked by SARS-CoV-2 to
inhibit IFN signaling, we tested whether Nup98 overexpression is able to revert the Orf6-mediated …

… ) of SARS-CoV-2 can directly manipulate localization and functions of nucleoporins. We found
that ORF6 protein disrupted nuclear … trafficking and led to nuclear accumulation of mRNA …

… However, interfering with nuclear trafficking using … of nuclear pathways caused by
SARS-CoV-2, including … and whether nuclear entry of the transcription factors is altered …

… to the nuclear translocation of nuclear factors (NF… nuclear DUSPs, which are key negative
regulators of MAPK and/or NF-κB pathways, are expressed to a lower level during a SARS-CoV…

… of specific transcription factors (eg, IRF-3, STAT-1/2)—would not be sufficient, the SARS-CoV-2 …
Conversely, we showed that nuclear translocation of the NF-κB transcription factor is not …