Tackling SARS-CoV-2: proposed targets and repurposed drugs
… , in absence of vaccines and drugs. The pathogenesis of SARS-CoV-2 is still being elucidated.
Identifying potential targets and repurposing drugs as therapeutic options is the need of …
Identifying potential targets and repurposing drugs as therapeutic options is the need of …
Repurposing existing drugs for the treatment of COVID-19/SARS-CoV-2 infection: A review describing drug mechanisms of action
… drugs, and it can be accomplished by repurposing drugs that are discussed in this article. In
this review, first, we will discuss drugs … In the next section, we will focus on the drugs that are …
this review, first, we will discuss drugs … In the next section, we will focus on the drugs that are …
[HTML][HTML] Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
… we screen a repurposing library of ∼3,000 drugs. Screening … validates 23 diverse antiviral
drugs. Extending our studies to … in drug sensitivity and entry pathways used by SARS-CoV-2 in …
drugs. Extending our studies to … in drug sensitivity and entry pathways used by SARS-CoV-2 in …
[HTML][HTML] New approaches and repurposed antiviral drugs for the treatment of the SARS-CoV-2 infection
LV Bauso, C Imbesi, G Irene, G Cali, A Bitto - Pharmaceuticals, 2021 - mdpi.com
… drugs are included 3CL protein inhibitors, RNA synthesis inhibitors and other small molecule
drugs which target the ability of SARS-COV… how some repurposed antiviral drugs, indicated …
drugs which target the ability of SARS-COV… how some repurposed antiviral drugs, indicated …
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer… - Science, 2021 - science.org
… drug discovery against this disease. We explore the prevalence of this confound in SARS-CoV-2
repurposing … hits rapidly so as to focus on drugs with genuine potential against COVID-…
repurposing … hits rapidly so as to focus on drugs with genuine potential against COVID-…
Repurposing antivirals as potential treatments for SARS-CoV-2: From SARS to COVID-19
D Gómez-Ríos, VA López-Agudelo… - Journal of Applied …, 2020 - japsonline.com
… here supports those drugs as feasible alternatives to face the SARS-CoV infection in the
short term, whereas more effective measures arise from the world scientific community. …
short term, whereas more effective measures arise from the world scientific community. …
A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2
A Simonis, SJ Theobald, G Fätkenheuer… - EMBO molecular …, 2021 - embopress.org
… In this comparative review, we focus on repurposed drugs with antiviral effects against
SARS‐CoV‐2 in cell‐based assays as those substances offer great opportunities for a treatment …
SARS‐CoV‐2 in cell‐based assays as those substances offer great opportunities for a treatment …
[HTML][HTML] An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors
… drugs that specifically target SARS-CoV-2. Until an effective vaccine is available, repurposing
FDA approved drugs … reduce the cost compared to de novo drug discovery. In this study we …
FDA approved drugs … reduce the cost compared to de novo drug discovery. In this study we …
Clinical trials of repurposed antivirals for SARS-CoV-2
MA Martinez - Antimicrobial agents and chemotherapy, 2020 - Am Soc Microbiol
… that either were effective in inhibiting SARS-CoV-2 in vitro or displayed some … human
coronavirus infections. Here, we discuss the results obtained with some of the repurposed drugs …
coronavirus infections. Here, we discuss the results obtained with some of the repurposed drugs …
Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements
A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
… The drug repurposing for SARS-CoV-2 is discussed in detail along with … SARS-CoV-2
with reference to case studies. The ongoing clinical trials both with respect to drug repurposing …
with reference to case studies. The ongoing clinical trials both with respect to drug repurposing …
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