Coronaviruses and sars-cov-2

M Hasöksüz, S Kilic, F Saraç - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
… -associated acute respiratory disease was labelled coronavirus disease 19 (COVID-19).
COVID-… virus was officially identified as severe acute respiratory syndrome coronavirus 2 (SARS-…

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
… Clearly, the intestine can also be infected by SARS-CoV-2, and gastrointestinal symptoms
are relatively frequent, yet it is unknown how intestinal infection contributes to severe COVID-…

[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
… In 2002 and 2012, respectively, two highly pathogenic coronaviruses with zoonotic origin,
severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory …

SARS-CoV-2: a storm is raging

SF Pedersen, YC Ho - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
… and immunological characteristics between moderate and severe COVID-19. The authors
… with severe COVID-19. Overall, this study characterized the cytokine storm in severe COVID-…

Coronaviruses and SARS-CoV-2: a brief overview

S Ludwig, A Zarbock - Anesthesia & Analgesia, 2020 - journals.lww.com
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and defined as the causal
agent of coronavirus … have basic knowledge of SARS-CoV-2 and the course of COVID-19 to …

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

SSA Karim, QA Karim - The lancet, 2021 - thelancet.com
… The principal concerns about omicron include whether it is more infectious or severe than
… to provide preliminary indications on transmissibility, severity, and immune escape. Omicron …

How does SARS-CoV-2 cause COVID-19?

NJ Matheson, PJ Lehner - Science, 2020 - science.org
… interaction between SARS-CoV-2 and ACE2 is critical to determining both tissue tropism
and progression from early SARS-CoV-2 infection to severe coronavirus disease 2019 (COVID-…

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

TS Rodrigues, KSG de Sá, AY Ishimoto… - Journal of Experimental …, 2021 - rupress.org
… to SARS-CoV-2 infection and is active in COVID-19 patients. Studying moderate and severe
COVID… in the sera correlated with the markers of COVID-19 severity, including IL-6 and LDH. …

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

CGK Ziegler, VN Miao, AH Owings, AW Navia, Y Tang… - Cell, 2021 - cell.com
SARS-CoV-2 RNA + host-target … to SARS-CoV-2, the direct viral targets of infection, and
suggests that failed nasal epithelial anti-viral immunity may underlie and precede severe COVID-…

Immune response to SARSCoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
… target for intervention to minimize the risk of severe disease. Some infectious agents, such
… of SARS-CoV-2 infection. Limited numbers of studies have focused on severe COVID-19 …