[HTML][HTML] Deepening of in silico evaluation of SARS-CoV-2 detection RT-qPCR assays in the context of new variants

M Gand, K Vanneste, I Thomas, S Van Gucht, A Capron… - Genes, 2021 - mdpi.com
… these assays are still performant to detect the virus that has evolved … silico for 11 primers
and probe sets using the bioinformatics tool SCREENED and 84,305 representative SARS-CoV-…

[HTML][HTML] Summary of the available molecular methods for detection of SARS-CoV-2 during the ongoing pandemic

F Arena, S Pollini, GM Rossolini… - International Journal of …, 2021 - mdpi.com
… Many suppliers declare the ability of their test to in silico detect the viral variants that were
circulating and included in freely available repositories (eg, NCBI Genbank and GISAID) at the …

[HTML][HTML] … of peptides with binding to the receptor binding domain (RBD) of the SARS-CoV-2 and their utility in bio-sensor development for SARS-CoV-2 detection

Y Badhe, R Gupta, B Rai - RSC advances, 2021 - pubs.rsc.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of
people across the globe and created not only a health emergency but also a financial crisis. …

[HTML][HTML] In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

IQ Phan, S Subramanian, D Kim, M Murphy, D Pettie… - Scientific reports, 2021 - nature.com
… serological study on SARS-CoV-2 proteins using LISP 4 and compared to our in-silico
predictions (Table 1). The experimental data appeared to validate our in-silico predictions for Nuc, …

[HTML][HTML] Use of whole genome sequencing data for a first in silico specificity evaluation of the RT-qPCR assays used for SARS-CoV-2 detection

M Gand, K Vanneste, I Thomas, S Van Gucht… - International Journal of …, 2020 - mdpi.com
silico study were obtained in the wet lab by Chan and colleagues, who detected SARS-CoV
RdRp gene that is considered strictly specific to SARS-CoV-2 [30]. This indicates that our in …

In silico detection of potential inhibitors from vitamins and their derivatives compounds against SARS-CoV-2 main protease by using molecular docking, molecular …

A Belhassan, S Chtita, H Zaki, M Alaqarbeh… - Journal of molecular …, 2022 - Elsevier
… caused by SARS-COV-2 virus of the coronavirus Family. The … active site of SARS-CoV-2
main protease was carried out. … with the active site of SARS-CoV-2 main protease enzyme. …

In silico detection of inhibitor potential of Passiflora compounds against SARS-Cov-2 (Covid-19) main protease by using molecular docking and dynamic analyses

S Yalçın, S Yalçınkaya, F Ercan - Journal of Molecular Structure, 2021 - Elsevier
SARS-Cov-2(Covid-19) is a new strain of coronavirus and was firstly emerged in December
2019 in Wuhan, China. Now, there is no known specific treatment of Covid-19 available. …

[HTML][HTML] Design and in silico validation of polymerase chain reaction primers to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

MJP Davi, SMB Jeronimo, JPMS Lima, DCF Lanza - Scientific Reports, 2021 - nature.com
detect many viral variants is imperative. In this work, we identified 26 conserved segments
(CS) in the SARS-CoV… We extended the analyses to include 211,833 SARS-CoV-2 sequences …

[HTML][HTML] In Silico Evaluation of CRISPR-Based Assays for Effective Detection of SARS-CoV-2

P Kaewsapsak, N Chantaravisoot, P Nimsamer… - Pathogens, 2022 - mdpi.com
SARS-CoV-2 detection have been developed and published during the past few years.
Nonetheless, SARS-CoV-… be affected by the high mutation rate of SARS-CoV-2. In this systematic …

[HTML][HTML] Utility of in silico-identified-peptides in spike-S1 domain and nucleocapsid of SARS-CoV-2 for antibody detection in COVID-19 patients and antibody …

K Cortés-Sarabia, VM Luna-Pineda… - Scientific Reports, 2022 - nature.com
… The main objective of in silico analysis is to identify … 19,20 ; however, in silico analysis to
identify novel epitopes that could be … of SARS-CoV-2 that could be used for antibody detection in …