A two-step process for in silico screening to assess the performance of qRTPCR kits against variant strains of SARS-CoV-2

S Gupta, A Kumar, N Gupta, DR Bharti, N Aggarwal… - BMC genomics, 2022 - Springer
… Though the screening process developed by us in the present study has considered
various possibilities for evaluation of qRTPCR kits for detection of SARS-CoV-2, but in silico

A rapid, specific, extraction-less, and cost-effective RT-LAMP test for the detection of SARS-CoV-2 in clinical specimens

FE Marino, E Proffitt, E Joseph, A Manoharan - PLoS One, 2022 - journals.plos.org
… used to detect the genes Orf1, E, and N of the SARS-CoV-2 virus are highly specific (SARS-CoV-2 …
Thus, both in silico and wet testing analysis showed a high specificity of the Prime …

[HTML][HTML] An in silico map of the SARS-CoV-2 RNA Structurome

RJ Andrews, JM Peterson, HS Haniff, J Chen… - BioRxiv, 2020 - ncbi.nlm.nih.gov
… S2a) are completely conserved between SARS-CoV and SARS-CoV-2. The corresponding
structured motifs detected in the negative strand are similarly conserved between …

[HTML][HTML] In silico approach to accelerate the development of mass spectrometry-based proteomics methods for detection of viral proteins: Application to COVID-19

C Jenkins, B Orsburn - BioRxiv, 2020 - biorxiv.org
… for the virus causing COVID-2 (SARS-CoV-2). Here we … as a SARS-CoV-2 screening method,
through the detection of viral peptides in proteolytically digested body fluids. Using in silico

[PDF][PDF] Design of CRISPR-based Targets for the Development of a Diagnostic Method for SARS-CoV-2: an in Silico Approach

AP Karlapudi, CV Thirupati, K Srirrama… - Eurasian Journal of …, 2020 - academia.edu
… for the detection of SARSCoV-2. However, computationally designed sgRNA requires to be
tested in vitro to demonstrate its potential and efficiency in detecting this novel coronavirus. …

In-silico approaches to detect inhibitors of the human severe acute respiratory syndrome coronavirus envelope protein ion channel

MK Gupta, S Vemula, R Donde, G Gouda… - Journal of …, 2021 - Taylor & Francis
detect difference between ‘SARS-CoV E’ and ‘SARS-CoV2 E’ protein. Subseqeuntly, sequence
of ‘SARS-… 5 × 29 is detected as the best homologous structure of human ‘SARS-CoV2 E’ …

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10

IH Eissa, MM Khalifa, EB Elkaeed, EE Hafez… - Molecules, 2021 - mdpi.com
In continuation of our previous effort, different in silico selection methods were applied to
310 naturally isolated metabolites that exhibited antiviral potentialities before. The applied …

C60 fullerene against SARS-CoV-2 coronavirus: an in silico insight

VV Hurmach, MO Platonov, SV Prylutska, P Scharff… - Scientific reports, 2021 - nature.com
… Based on WHO reports the new SARS-CoV-2 coronavirus is currently widespread all over …
of the potential binding mechanism between SARS-CoV-2 proteins 3CLpro and RdRp with C …

… genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight

MI Khan, ZA Khan, MH Baig, I Ahmad, AEA Farouk… - PLoS …, 2020 - journals.plos.org
SARS-CoV-2 genome reported from 13 different countries, identification of mutations in major
coronavirus proteins of these different SARS-CoV-2 … We detected one amino acid mutation …

In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs

SK Mondal, S Mukhoty, H Kundu, S Ghosh… - Computers in Biology …, 2021 - Elsevier
SARS-CoV-2 and other SARS-CoVs (SARS coronavirus Shanghai QXC2, … detected main
fluctuations in the last 20 amino acid residues of nsp12, while minor movements were detected