[HTML][HTML] The spike protein of SARS-CoV—a target for vaccine and therapeutic development
L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
… on the spike (S) protein of severe acute respiratory syndrome-coronavirus (SARS-CoV) as a
… for the development of vaccines and therapeutics for the prevention and treatment of SARS. …
… for the development of vaccines and therapeutics for the prevention and treatment of SARS. …
Structure of SARS-CoV-2 spike protein
… of the structure of the SARS-CoV-2 S protein and discuss the … of coronavirus S proteins,
including the full-length SARS-CoV… ID: 7KRR ), the stabilized soluble SARS-CoV-2 S trimer in the …
including the full-length SARS-CoV… ID: 7KRR ), the stabilized soluble SARS-CoV-2 S trimer in the …
[PDF][PDF] Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant
L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch… - Cell, 2020 - cell.com
The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide,
reaching near fixation in a matter of months. Here we show that D614G was more infectious …
reaching near fixation in a matter of months. Here we show that D614G was more infectious …
[HTML][HTML] Domains and functions of spike protein in Sars-Cov-2 in the context of vaccine design
X Xia - Viruses, 2021 - mdpi.com
… SARS-CoV-2 uses its trimeric spike protein for binding to host angiotensin-converting … This
is a multi-step process involving three separate S protein cleavage events to prime the SARS-…
is a multi-step process involving three separate S protein cleavage events to prime the SARS-…
Human SARS CoV‐2 spike protein mutations
L Guruprasad - Proteins: Structure, Function, and Bioinformatics, 2021 - Wiley Online Library
… in 8155 proteins among 10333 human SARS-CoV-2 spike protein sequences analyzed in
… for all the spike proteins. The mutation sites are distributed over whole length of the protein …
… for all the spike proteins. The mutation sites are distributed over whole length of the protein …
[HTML][HTML] Dynamics of the ACE2–SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms
… of the spike (S) protein of SARS-CoV-2 and SARS-CoV bound to … Our results indicate that
SARS-CoV-2 and SARS-CoV … the residues of SARS-CoV-2 and SARS-CoV that consistently …
SARS-CoV-2 and SARS-CoV … the residues of SARS-CoV-2 and SARS-CoV that consistently …
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
… The most striking feature of the coronavirus is the club-shaped spike protein projecting from
… on the viral Spike protein have been found in circulating clinical SARS-CoV-2 strains (Korber …
… on the viral Spike protein have been found in circulating clinical SARS-CoV-2 strains (Korber …
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
S Belouzard, VC Chu… - Proceedings of the …, 2009 - National Acad Sciences
… To investigate the possibility that additional, possibly cryptic, cleavage sites exist within the
coronavirus spike protein, we examined a comprehensive selection of spike proteins from …
coronavirus spike protein, we examined a comprehensive selection of spike proteins from …
[HTML][HTML] Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference
Y Zhang, T Li, L Fu, C Yu, Y Li, X Xu, Y Wang, H Ning… - FEBS letters, 2004 - Elsevier
… of Spike protein from SARS-CoV-infected cells or tissues. In this report we used the
recombinant Spike protein cDNA from the SARS-CoV genome and expressed the protein in 293T …
recombinant Spike protein cDNA from the SARS-CoV genome and expressed the protein in 293T …
Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies
… Severe acute respiratory syndrome coronavirus (SARS-CoV) … The heavily glycosylated
SARS-CoV spike (S) protein binds … system could block the S protein and angiotensin-converting …
SARS-CoV spike (S) protein binds … system could block the S protein and angiotensin-converting …
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