[HTML][HTML] Main clinical features of COVID-19 and potential prognostic and therapeutic value of the microbiota in SARS-CoV-2 infections
Y He, J Wang, F Li, Y Shi - Frontiers in Microbiology, 2020 - frontiersin.org
… The communication between the microbiota and SARS-CoV-2 and … SARS-CoV-2 infection
may help predict patient outcomes and allow the development of microbiota-based therapies…
may help predict patient outcomes and allow the development of microbiota-based therapies…
[HTML][HTML] The added value of pirfenidone to fight inflammation and fibrotic state induced by SARS-CoV-2: Anti-inflammatory and anti-fibrotic therapy could solve the …
F Ferrara, G Granata, C Pelliccia, R La Porta… - European Journal of …, 2020 - Springer
… In this article, we consider the role of antifibrotic therapy with pirfenidone in patients with
SARS-CoV-2 infection on going or in the stage of postinfection with pulmonary fibrotic …
SARS-CoV-2 infection on going or in the stage of postinfection with pulmonary fibrotic …
Potential therapeutic targets and promising drugs for combating SARS‐CoV‐2
H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
… ACE2 as an important therapeutic target of SARS-CoV-2 entry … summarize the potential
therapeutic targets involved in the … ) indicated the potential therapeutic value of RNA aptamers …
therapeutic targets involved in the … ) indicated the potential therapeutic value of RNA aptamers …
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Z Lv, YQ Deng, Q Ye, L Cao, CY Sun, C Fan, W Huang… - Science, 2020 - science.org
… Pseudovirus neutralization assays revealed that H014 has potent neutralizing activities:
a 50% neutralizing concentration value (IC 50 ) of 3 nM and 1 nM against SARS-CoV-2 and …
a 50% neutralizing concentration value (IC 50 ) of 3 nM and 1 nM against SARS-CoV-2 and …
Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus …
S Kumar, P Kashyap, S Chowdhury, S Kumar… - Phytomedicine, 2021 - Elsevier
… They are eco-friendly molecules which can have therapeutic value. Several phytochemicals
such as alkaloids, terpenoids, saponins,and polyphenols are reported to possess antiviral …
such as alkaloids, terpenoids, saponins,and polyphenols are reported to possess antiviral …
Broad‐spectrum prodrugs with anti‐SARS‐CoV‐2 activities: Strategies, benefits, and challenges
Z Wang, L Yang - Journal of medical virology, 2022 - Wiley Online Library
… of SARS-CoV-2 infection, and additional potent anti-SARS-CoV-… clinical challenges of
anti-SARS-CoV-2 agents to provide … needed to assess the therapeutic value of FVP in COVID-19. …
anti-SARS-CoV-2 agents to provide … needed to assess the therapeutic value of FVP in COVID-19. …
Therapeutic approaches for SARS-CoV-2 infection
A Gupta, A Pradhan, VK Maurya, S Kumar, A Theengh… - Methods, 2021 - Elsevier
… In this article, we summarize all the therapeutic antiviral … , vaccines, plasma therapy, various
adjunct therapies, and phage … to block SARS-CoV-2 virus infection, with an IC 50 value of …
adjunct therapies, and phage … to block SARS-CoV-2 virus infection, with an IC 50 value of …
Modelling SARS-CoV-2 dynamics: implications for therapy
… parameter values (Table 1), we conducted in silico experiments for possible anti-SARS-CoV-2
therapies to investigate the expected outcome under hypothetical drug therapies (or …
therapies to investigate the expected outcome under hypothetical drug therapies (or …
Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress
MJ Hossain, SMA Rahman - … Review of Anti-Infective Therapy, 2021 - Taylor & Francis
… [Citation22] assessed the in vitro cytotoxic properties of NTZ against SARS-CoV-2 with an
EC 50 value of 2.12 µM, determined by CCK-8 assays on Vero E6 cells. The EC 50 values for …
EC 50 value of 2.12 µM, determined by CCK-8 assays on Vero E6 cells. The EC 50 values for …
Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19
… -2 RBD, SBP-1 was found to potently bind to the SARS-CoV-2 RBD with a K D value of 47
nM, … These proteases have been confirmed as valuable therapeutic targets, and the inhibitors …
nM, … These proteases have been confirmed as valuable therapeutic targets, and the inhibitors …
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