SARS-CoV-2 variant vaccine boosters trial: preliminary analyses

AR Branche, NG Rouphael, DJ Diemert, AR Falsey… - MedRxiv, 2022 - medrxiv.org
SARS-CoV-2 variant vaccines. Methods This phase 2 open-label, randomized trial enrolled
healthy adults previously vaccinated with a SARS-CoV-… COVID19 mRNA vaccine arms (50µg …

Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis

A Choi, M Koch, K Wu, L Chu, LZ Ma, A Hill, N Nunna… - Nature medicine, 2021 - nature.com
… The emergence of SARS-CoV-2 variants of … of booster doses and variant-specific vaccines.
Clinical trial participants who received a two-dose primary series of the COVID-19 vaccine

Effectiveness of homologous and heterologous booster doses for an inactivated SARS-CoV-2 vaccine: a large-scale prospective cohort study

A Jara, EA Undurraga, JR Zubizarreta… - The Lancet Global …, 2022 - thelancet.com
… the effectiveness of booster doses for SARS-CoV-2 vaccines. … mRNA vaccine BNT162b2
compared with the primary vaccination … of testing positive for SARS-CoV-2 infection among …

Effect of mRNA vaccine boosters against SARS-CoV-2 Omicron infection in Qatar

LJ Abu-Raddad, H Chemaitelly… - … England Journal of …, 2022 - Mass Medical Soc
… As booster vaccination was being scaled up, the omicron … of SARS-CoV-2 infections in
Qatar. We investigated the effectiveness of booster vaccination against symptomatic SARS-CoV-2 …

Booster vaccination to reduce SARS-CoV-2 transmission and infection

A Wald - Jama, 2022 - jamanetwork.com
… This was definitely true for the original SARS-CoV-2 strain 10 … load declines more rapidly in
vaccinated individuals than in … Thus, with SARS-CoV-2 variants of concern, booster vaccine

[HTML][HTML] Heterologous SARS-CoV-2 booster vaccinations–preliminary report

RL Atmar, KE Lyke, ME Deming, LA Jackson… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… but are restricted to homologous mRNA vaccines. We evaluated homologous and heterologous
booster vaccination in persons who had received an EUA Covid-19 vaccine regimen. …

Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose

C Kuhlmann, CK Mayer, M Claassen, T Maponga… - The Lancet, 2022 - thelancet.com
… for SARS-CoV-2 by PCR and provided records of complete vaccination, including booster or
third, … using homologous (n=5) and heterologous (n=2) vaccination courses (appendix p 3). …

COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
… basis and clinical impact of SARS-CoV-2 variants and … vaccine booster regimens against
different SARS-CoV-2 strains. Additionally, we reviewed potential mechanisms of vaccine-…

Preliminary analysis of safety and immunogenicity of a SARS-CoV-2 variant vaccine booster

K Wu, A Choi, M Koch, LZ Ma, A Hill, N Nunna… - MedRxiv, 2021 - medrxiv.org
vaccines, designed to target emerging SARS-CoV-2 variants as booster vaccines in participants
previously vaccinated … two doses of the prototype vaccine, mRNA-1273. The modified …

Waning immunity to SARS-CoV-2: implications for vaccine booster strategies

DM Altmann, RJ Boyton - The lancet respiratory medicine, 2021 - thelancet.com
… in the pandemic, decisions on booster programmes represent real-life choices that sit at
the interface between immunological research and epidemiology data on SARS-CoV-2-related …