[HTML][HTML] Structure of SARS-CoV-2 membrane protein essential for virus assembly

Z Zhang, N Nomura, Y Muramoto, T Ekimoto… - Nature …, 2022 - nature.com
assembly and morphogenesis. However, the process of M protein-driven virus assembly
Here, we report the cryo-electron microscopy structure of the SARS-CoV-2 M protein in two …

[HTML][HTML] A structural view of the SARS-CoV-2 virus and its assembly

NJ Hardenbrook, P Zhang - Current opinion in virology, 2022 - Elsevier
… structural analysis of SARS-CoV-2. Here, we review the structural work on the SARS-CoV-2
virus and viral components, as well as its cellular assembly process, highlighting some …

[PDF][PDF] Properties of coronavirus and SARS-CoV-2

YA Malik - The Malaysian journal of pathology, 2020 - mjpath.org.my
… in viral assembly and budding. The N protein is the only one that binds to the RNA genome
and is also involved in viral assembly … Attachment of the virus to the host cell is initiated by …

Betacoronavirus assembly: clues and perspectives for elucidating SARS-CoV-2 particle formation and egress

D Bracquemond, D Muriaux - MBio, 2021 - Am Soc Microbiol
coronavirus replication that lead to the assembly of new viral particles, starting with the location
of viral … FIG 2 Proposed model of SARS-CoV-2 replication focused on virus assembly and …

[HTML][HTML] A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells

L Du, F Deiter, MS Bouzidi, JN Billaud… - Communications …, 2024 - nature.com
assembly screen, was recently shown to target host protein assembly machinery in a manner
specific to viral assembly. … of PAV-104 to inhibit SARS-CoV-2 replication in human airway …

SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

KM Scherer, L Mascheroni, GW Carnell… - Science …, 2022 - science.org
… of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication within cells. …
virus assembly by visualizing the spatiotemporal dynamics of the four structural SARS-CoV-2 …

[HTML][HTML] Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

E Murigneux, L Softic, C Aubé, C Grandi… - Nature …, 2024 - nature.com
… , the assembly and egress of newly formed virions are less understood. To identify host
proteins involved in viral morphogenesis, we characterize the proteome of SARS-CoV-2 virions …

[HTML][HTML] Molecular architecture of the SARS-CoV-2 virus

H Yao, Y Song, Y Chen, N Wu, J Xu, C Sun, J Zhang… - Cell, 2020 - cell.com
… elucidation of SARS-CoV-2 proteins, the detailed architecture of the intact virus remains to
be unveiled. Here we report the molecular assembly of the authentic SARS-CoV-2 virus using …

Architecture and self‐assembly of the SARSCoV‐2 nucleocapsid protein

Q Ye, AMV West, S Silletti, KD Corbett - Protein Science, 2020 - Wiley Online Library
… agent, the SARS-CoV-2 coronavirus. Here, we examine the architecture and self-assembly
properties of the SARS-CoV-2 nucleocapsid protein, which packages viral RNA into new …

[HTML][HTML] Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress

L Mendonça, A Howe, JB Gilchrist, Y Sheng… - Nature …, 2021 - nature.com
SARS-CoV-2 structural events – eg viral RNA transport portals, virus assembly intermediates,
virus … -2 replication process in the native cellular context is scarce 4,27 , and viral assembly