Characterization of viral proteins encoded by the SARS-coronavirus genome

YJ Tan, SG Lim, W Hong - Antiviral research, 2005 - Elsevier
… in all coronaviruses, and are important for viral assembly and (c) expression and functional
… by SARS-CoV. A comparison of the properties of these three groups of SARS-CoV proteins …

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

S Klein, M Cortese, SL Winter… - Nature …, 2020 - nature.com
assembled S trimers in lumenal cisternae do not alone induce membrane bending but
laterally reorganize on the envelope during virion assembly… morphology, virus assembly, and …

Benchmarking and Assessment of Eight De Novo Genome Assemblers on Viral Next-Generation Sequencing Data, Including the SARS-CoV-2

AK Gupta, M Kumar - OMICS: A Journal of Integrative Biology, 2022 - liebertpub.com
… report viral assembly benchmarks and performance on viral … and benchmarking of assembly
software on viral datasets from … data of eight different viruses, including SARS-CoV-2 (Table …

Construction of SARS-CoV-2 virus-like particles in plant

KB Moon, JH Jeon, H Choi, JS Park, SJ Park, HJ Lee… - Scientific reports, 2022 - nature.com
SARS-CoV-2 VLPs can be successfully assembled by co-expressing three important viral
… The shape and size of plant-derived VLPs are similar to native SARS-CoV-2 VLPs without …

Structure of SARS-CoV-2 M protein in lipid nanodiscs

KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth… - Elife, 2022 - elifesciences.org
… in a simple lipid bilayer and support a role for M homodimers in scaffolding viral assembly.
Together, these results provide insight into roles for M in coronavirus assembly and structure. …

Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
SARS-CoV-2 S protein is cleaved by host proteases into two subunits, a receptor-binding
fragment (S1) and a fusion fragment (S2), during biogenesis or virus assembly. The S1 subunit …

SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

A Jack, LS Ferro, MJ Trnka, E Wehri, A Nadgir… - PLoS …, 2021 - journals.plos.org
… N condensates may also sequester the viral assemblies from the immune response of the
host cell [8]. For example, N protein interacts with stress granule proteins G3BP1 and G3BP2 …

SARS-CoV-2 N protein antagonizes stress granule assembly and IFN production by interacting with G3BPs to facilitate viral replication

H Liu, Y Bai, X Zhang, T Gao, Y Liu, E Li… - Journal of …, 2022 - Am Soc Microbiol
… Using live SARS-CoV-2 viruses, this study provides solid evidence showing that SARS-CoV-2
NP … IMPORTANCE In this study, by in vitro assay and live SARS-CoV-2 virus infection, we …

[HTML][HTML] Molecular architecture and dynamics of SARS-CoV-2 envelope by integrative modeling

W Pezeshkian, F Grünewald, O Narykov, S Lu… - Structure, 2023 - cell.com
… into large, filament-like, macromolecular assemblies with distinct molecular patterns. These
… of these viruses. The virion particles of SARS-CoV-2 and closely related viruses are formed …

[HTML][HTML] Efficient assembly and release of SARS coronavirus-like particles by a heterologous expression system

E Mortola, P Roy - FEBS letters, 2004 - Elsevier
… These smooth surfaced particles are probably an intermediate particle in virus assembly.
The formation of VLPs by these two proteins has been reported for other coronaviruses [16], [17]…