[PDF][PDF] Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice

M You, RV Considine, TC Leone, DP Kelly… - …, 2005 - Wiley Online Library
… and enhanced activity of a mouse adiponectin promoter. In conclusion, the protective action
of saturated fat against the development of alcoholic fatty liver in mice is partially mediated …

… administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver

D Nigro, F Menotti, AS Cento, L Serpe… - The Journal of …, 2017 - Elsevier
… Our results indicate that saturated fats and fructose in the diet exert dissimilar effects on liver
lipid metabolism. We show that hepatic lipid accumulation in HFAT mice is due to the lack of …

A high-fat, high-oleic diet, but not a high-fat, saturated diet, reduces hepatic α-linolenic acid and eicosapentaenoic acid content in mice

MJ Picklo, EJ Murphy - Lipids, 2016 - Springer
… of saturated fatty acids (SFA) and monounsaturated fatty acids (… development of fatty liver
in mice fed high-fat diets. However, … to the development of fatty liver needs more investigation. …

Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars

PK Luukkonen, S Sädevirta, Y Zhou, B Kayser… - Diabetes …, 2018 - Am Diabetes Assoc
… High saturated fat–feeding in mice stimulates lipolysis via inflammatory mediators (6). In
keeping with such data, we found upregulation of multiple inflammation-related pathways in the …

[HTML][HTML] Saturated and unsaturated dietary fats differentially modulate ethanol-induced changes in gut microbiome and metabolome in a mouse model of alcoholic …

IA Kirpich, J Petrosino, N Ajami, W Feng… - The American journal of …, 2016 - Elsevier
fat diet and ethanol but not a saturated fat diet and ethanol. Compared with a saturated fat
diet and ethanol, an unsaturated fat … in unsaturated fats enhanced alcohol-induced liver injury …

Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis

JE Mells, PP Fu, P Kumar, T Smith, SJ Karpen… - The Journal of nutritional …, 2015 - Elsevier
… To examine whether stellate cell activation was significant in the HFTFX-fed mice, we stained
liver sections with tagged anti-alpha smooth muscle actin (α-SMA) antibodies, a marker of …

… in liver PPARγ2 is an initial event to induce fatty liver in response to a diet high in butter: PPARγ2 knockdown improves fatty liver induced by high-saturated fat

T Yamazaki, S Shiraishi, K Kishimoto, S Miura… - The Journal of nutritional …, 2011 - Elsevier
… , saturated fatty acid-rich oil induced fatty liver in mice, and … of saturated fatty acid-rich oil
(butter) induces fatty liver in mice. … that the development of fatty liver rather than obesity is more …

Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease

AK Leamy, RA Egnatchik, JD Young - Progress in lipid research, 2013 - Elsevier
… In fact, analysis of liver tissues from both high-fat fed mice and human NAFLD patients …
Many studies have demonstrated that saturated fatty acids are more toxic than their unsaturated …

[HTML][HTML] Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition

MJJ Ronis, S Korourian, M Zipperman, R Hakkak… - The Journal of …, 2004 - Elsevier
saturated fat also decreased liver triglyceride, PUFA, and total FFA concentrations (P < 0.05).
Increases in dietary saturated fat increased liver … in p47-knockout mice lacking a critical …

[HTML][HTML] Effects of dietary fat and saturated fat content on liver fat and markers of oxidative stress in overweight/obese men and women under weight-stable conditions

A Marina, AD Von Frankenberg, S Suvag, HS Callahan… - Nutrients, 2014 - mdpi.com
… that high fat/saturated fat diets (HFD) increase liver fat and … on a low fat/low saturated fat
diet (LFD) decreased liver fat … of four weeks on a LFD to decrease liver fat, but no effect of a …